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Lab Policy and Culture
Photo credit: Juliana Sohn Our mission & ethos: Our mission is to uncover biological knowledge and new medicines by developing advanced methods to quantify and mine the rich information in images. Together, our team explores the inner workings of biological systems and makes discoveries that can...
Previously Released Versions of CellProfiler Analyst
Release Version Platform 3.0.4 Mac (up to OSX11), Mac (OSX12+) Windows 3.0.2 Mac Windows 2.2.1 Mac* Windows 2.0, r11710 Mac Windows 2.0, r11306 Mac Windows 2.0, r10530 Mac Windows 2.0, r9128 Mac WindowsXP 2.0, r8634 WindowsXP 2.0, r8582 Mac 1.1 Linux Mac WindowsXP 1.0 Linux Mac WindowsXP *(only...
Funding
Since 2003, grants have been provided by...
Next-generation characterization of the Cancer Cell Line Encyclopedia
Ghandi, Mahmoud, Franklin Huang, Judit Jané-Valbuena, Gregory Kryukov, Christopher Lo, Robert McDonald, Jordi Barretina, et al. 2019. “Next-Generation Characterization of the Cancer Cell Line Encyclopedia”. Nature 569 (7757): 503-8.
The landscape of cancer cell line metabolism
Li, Haoxin, Shaoyang Ning, Mahmoud Ghandi, Gregory Kryukov, Shuba Gopal, Amy Deik, Amanda Souza, et al. 2019. “The Landscape of Cancer Cell Line Metabolism”. Nat Med 25 (5): 850-60.
Oncogenic Hijacking of the Stress Response Machinery in T cell Acute Lymphoblastic Leukemia
Kourtis, Nikos, Charalampos Lazaris, Kathryn Hockemeyer, Juan Carlos Balandrán, Alejandra R. Jimenez, Jasper Mullenders, Yixiao Gong, et al. 2018. “Oncogenic Hijacking of the Stress Response Machinery in T Cell Acute Lymphoblastic Leukemia”. Nat Med 24: 1157-66.
Stratification of TAD Boundaries Reveals Preferential Insulation of Super-enhancers by Strong Boundaries
Gong, Yixiao, Charalampos Lazaris, Theodore Sakellaropoulos, Aurelie Lozano, Prabhanjan Kambadur, Panagiotis Ntziachristos, Iannis Aifantis, and Aristotelis Tsirigos. 2018. “Stratification of TAD Boundaries Reveals Preferential Insulation of Super-Enhancers by Strong Boundaries”. Nat Commun 9: 542-42.
Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2
Modrek, Aram S., Danielle Golub, Themasap Khan, Devin Bready, Jod Prado, Christopher Bowman, Jingjing Deng, et al. 2017. “Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2”. Cell Rep 21: 1267-80.
Regulation of Transcriptional Elongation in Pluripotency and cell Differentiation by the PHD-finger Protein Phf5a
Strikoudis, Alexandros, Charalampos Lazaris, Thomas Trimarchi, Antonio L. Galvao Neto, Yan Yang, Panagiotis Ntziachristos, Scott Rothbart, et al. 2016. “Regulation of Transcriptional Elongation in Pluripotency and Cell Differentiation by the PHD-Finger Protein Phf5a”. Nat Cell Biol 18: 1127-38.