A molecular signature of metastasis in primary solid tumors
Ramaswamy, S., K. N. Ross, E. S. Lander, and T. R. Golub. 2003. “A Molecular Signature of Metastasis in Primary Solid Tumors”. Nat Genet 33: 49-54.
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Recurrent and functional regulatory mutations in breast cancer
Rheinbay, E., P. Parasuraman, J. Grimsby, G. Tiao, J. M. Engreitz, J. Kim, M. S. Lawrence, et al. 2017. “Recurrent and Functional Regulatory Mutations in Breast Cancer”. Nature 547: 55-60.
Genetic modifiers of EGFR dependence in non-small cell lung cancer
Sharifnia, T., V. Rusu, F. Piccioni, M. Bagul, M. Imielinski, A. D. Cherniack, C. S. Pedamallu, et al. 2014. “Genetic Modifiers of EGFR Dependence in Non-Small Cell Lung Cancer”. Proc Natl Acad Sci U S A 111: 18661-6.
Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER(+) breast cancer
Shee, K., A. Jiang, F. S. Varn, S. Liu, N. A. Traphagen, P. Owens, C. X. Ma, et al. 2019. “Cytokine Sensitivity Screening Highlights BMP4 Pathway Signaling As a Therapeutic Opportunity in ER(+) Breast Cancer”. FASEB J 33: 1644-57.
An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray
Ebert, B. L., M. M. Lee, J. L. Pretz, A. Subramanian, R. Mak, T. R. Golub, and C. A. Sieff. 2005. “An RNA Interference Model of RPS19 Deficiency in Diamond-Blackfan Anemia Recapitulates Defective Hematopoiesis and Rescue by Dexamethasone: Identification of Dexamethasone-Responsive Genes by Microarray”. Blood 105: 4620-6.
Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
Ebert, B. L., J. Pretz, J. Bosco, C. Y. Chang, P. Tamayo, N. Galili, A. Raza, et al. 2008. “Identification of RPS14 As a 5q- Syndrome Gene by RNA Interference Screen”. Nature 451: 335-9.
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
Filbin, M. G., I. Tirosh, V. Hovestadt, M. L. Shaw, L. E. Escalante, N. D. Mathewson, C. Neftel, et al. 2018. “Developmental and Oncogenic Programs in H3K27M Gliomas Dissected by Single-Cell RNA-Seq”. Science 360: 331-35.
Next-generation characterization of the Cancer Cell Line Encyclopedia
Ghandi, M., F. W. Huang, J. Jane-Valbuena, G. V. Kryukov, C. C. Lo, 3rd McDonald E. R., J. Barretina, et al. 2019. “Next-Generation Characterization of the Cancer Cell Line Encyclopedia”. Nature 569: 503-8.
Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia
Golub, T. R., A. Goga, G. F. Barker, D. E. Afar, J. McLaughlin, S. K. Bohlander, J. D. Rowley, O. N. Witte, and D. G. Gilliland. 1996. “Oligomerization of the ABL Tyrosine Kinase by the Ets Protein TEL in Human Leukemia”. Mol Cell Biol 16: 4107-16.
Multiplex cytological profiling assay to measure diverse cellular states
Gustafsdottir, S. M., V. Ljosa, K. L. Sokolnicki, J. Anthony Wilson, D. Walpita, M. M. Kemp, K. Petri Seiler, et al. 2013. “Multiplex Cytological Profiling Assay to Measure Diverse Cellular States”. PLoS One 8: e80999.