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Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
Wu, Tiffany, Borislav Dejanovic, Vineela D Gandham, Alvin Gogineni, Rose Edmonds, Stephen Schauer, Karpagam Srinivasan, et al. 2019. “Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.”. Cell Reports 28 (8): 2111-2123.e6.
Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function.
Hackos, David H, Patrick J Lupardus, Teddy Grand, Yelin Chen, Tzu-Ming Wang, Paul Reynen, Amy Gustafson, et al. 2016. “Positive Allosteric Modulators of GluN2A-Containing NMDARs With Distinct Modes of Action and Impacts on Circuit Function.”. Neuron 89 (5): 983-99.
Local pruning of dendrites and spines by caspase-3-dependent and proteasome-limited mechanisms.
Ertürk, Ali, Yuanyuan Wang, and Morgan Sheng. 2014. “Local Pruning of Dendrites and Spines by Caspase-3-Dependent and Proteasome-Limited Mechanisms.”. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 34 (5): 1672-88.
Long-term depression: a cell biological view.
Sheng, Morgan, and Ali Ertürk. 2014. “Long-Term Depression: A Cell Biological View.”. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 369 (1633): 20130138.
Caspases in synaptic plasticity.
Li, Zheng, and Morgan Sheng. 2012. “Caspases in Synaptic Plasticity.”. Molecular Brain 5: 15.
Kyla Jacobs
she/her
Sheng Lab
Proline-rich tyrosine kinase 2 regulates hippocampal long-term depression.
Hsin, Honor, Myung Jong Kim, Chi-Fong Wang, and Morgan Sheng. 2010. “Proline-Rich Tyrosine Kinase 2 Regulates Hippocampal Long-Term Depression.”. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 30 (36): 11983-93.
Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines.
Bingol, Baris, Chi-Fong Wang, David Arnott, Dongmei Cheng, Junmin Peng, and Morgan Sheng. 2010. “Autophosphorylated CaMKIIalpha Acts As a Scaffold to Recruit Proteasomes to Dendritic Spines.”. Cell 140 (4): 567-78.