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Shengmiao Chen

Person: Postdoctoral Associate, Dana Farber Cancer Institute

Shengmiao Chen, PhD Shengmiao is a postdoc in the Raghavan Lab. During his PhD, he focused on discovering cancer targets through CRISPR screening and elucidating molecular mechanisms. His current research aims to identify potential therapeutic targets for pancreatic cancer through screening. He...

For Individuals and Families

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Have a direct impact on the future of bipolar research. Asian Bipolar Genetics Network (A-BIG-NET) is a study to advance our understanding of the genetic basis of bipolar disorder in Asian populations, leading to improved healthcare outcomes and reduced disparities in mental health treatment. Learn...

ABIGNET

Asian Bipolar Genetics Network (A-BIG-NET) is a study to advance our understanding of the genetic basis of bipolar disorder in Asian populations.

Preguntas frecuentes

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Explore esta página para hallar respuestas a preguntas frecuentes. También le recomendamos que lea las demás páginas de este sitio web. Si no encuentra respuesta a su pregunta, escríbanos por correo electrónico a raregenomes@broadinstitute.org o llámenos por teléfono al 617-714-7395 (Línea gratuita...

The Francisella O-antigen mediates survival in the macrophage cytosol via autophagy avoidance.

Publication: Journal Article

Case, Elizabeth Di Russo, Audrey Chong, Tara D Wehrly, Bryan Hansen, Robert Child, Seungmin Hwang, Herbert W Virgin, and Jean Celli. 2014. “The Francisella O-Antigen Mediates Survival in the Macrophage Cytosol via Autophagy Avoidance.”. Cellular Microbiology 16 (6): 862-77.

TANK-binding kinase-1 plays an important role during in vitro and in vivo type I IFN responses to DNA virus infections.

Publication: Journal Article

Miyahira, Andrea K, Arash Shahangian, Seungmin Hwang, Ren Sun, and Genhong Cheng. 2009. “TANK-Binding Kinase-1 Plays an Important Role During in Vitro and in Vivo Type I IFN Responses to DNA Virus Infections.”. Journal of Immunology (Baltimore, Md. : 1950) 182 (4): 2248-57.

High-resolution functional profiling of a gammaherpesvirus RTA locus in the context of the viral genome.

Publication: Journal Article

Arumugaswami, Vaithilingaraja, Ronika Sitapara, Seungmin Hwang, Moon Jung Song, Tuyet Ngoc Ho, Nancy Qi Su, Eric Y Sue, et al. 2009. “High-Resolution Functional Profiling of a Gammaherpesvirus RTA Locus in the Context of the Viral Genome.”. Journal of Virology 83 (4): 1811-22.

Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 RTA reactivates murine gammaherpesvirus 68 from latency.

Publication: Journal Article

Rickabaugh, Tammy M, Helen J Brown, Ting-Ting Wu, Moon Jung Song, Seungmin Hwang, Hongyu Deng, Katherine Mitsouras, and Ren Sun. 2005. “Kaposi’s Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 RTA Reactivates Murine Gammaherpesvirus 68 from Latency.”. Journal of Virology 79 (5): 3217-22.

The Kaposi's sarcoma-associated herpesvirus K8 protein interacts with CREB-binding protein (CBP) and represses CBP-mediated transcription.

Publication: Journal Article

Hwang, S, Y Gwack, H Byun, C Lim, and J Choe. 2001. “The Kaposi’s Sarcoma-Associated Herpesvirus K8 Protein Interacts With CREB-Binding Protein (CBP) and Represses CBP-Mediated Transcription.”. Journal of Virology 75 (19): 9509-16.

Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway.

Publication: Journal Article

Chong, Audrey, Tara D Wehrly, Robert Child, Bryan Hansen, Seungmin Hwang, Herbert W Virgin, and Jean Celli. 2012. “Cytosolic Clearance of Replication-Deficient Mutants Reveals Francisella Tularensis Interactions With the Autophagic Pathway.”. Autophagy 8 (9): 1342-56.