Postsynaptic signaling and plasticity mechanisms.
Sheng, Morgan, and Myung Jong Kim. 2002. “Postsynaptic Signaling and Plasticity Mechanisms.”. Science (New York, N.Y.) 298 (5594): 776-80.
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A synaptic molecular dependency network in knockdown of autism- and schizophrenia-associated genes revealed by multiplexed imaging.
Falkovich, Reuven, Eric W Danielson, Karen Perez de Arce, Eike-C Wamhoff, Juliana Strother, Anna P Lapteva, Morgan Sheng, Jeffrey R Cottrell, and Mark Bathe. 2023. “A Synaptic Molecular Dependency Network in Knockdown of Autism- and Schizophrenia-Associated Genes Revealed by Multiplexed Imaging.”. Cell Reports 42 (5): 112430.
Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice
Farsi, Zohreh, and Morgan H Sheng. 2023. “Brain-Region-Specific Changes in Neurons and Glia and Dysregulation of Dopamine Signaling in Grin2a Mutant Mice”. Neuroresource.
Multiple sclerosis risk gene Mertk is required for microglial activation and subsequent remyelination.
Shen, Kimberle, Mike Reichelt, Roxanne Kyauk V, Hai Ngu, Yun-An A Shen, Oded Foreman, Zora Modrusan, Brad A Friedman, Morgan Sheng, and Tracy J Yuen. 2021. “Multiple Sclerosis Risk Gene Mertk Is Required for Microglial Activation and Subsequent Remyelination.”. Cell Reports 34 (10): 108835.
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology.
Lee, Seung-Hye, William J Meilandt, Luke Xie, Vineela D Gandham, Hai Ngu, Kai H Barck, Mitchell G Rezzonico, et al. 2021. “Trem2 Restrains the Enhancement of Tau Accumulation and Neurodegeneration by β-Amyloid Pathology.”. Neuron 109 (8): 1283-1301.e6.
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.
Dejanovic, Borislav, Melanie A Huntley, Ann De Mazière, William J Meilandt, Tiffany Wu, Karpagam Srinivasan, Zhiyu Jiang, et al. 2018. “Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies.”. Neuron 100 (6): 1322-1336.e7.
USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-Dependent Protein Levels.
Campbell, Meghan Kerrisk, and Morgan Sheng. 2018. “USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-Dependent Protein Levels.”. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 38 (23): 5289-5301.
Microglia in Alzheimer's disease.
Hansen, David, V, Jesse E Hanson, and Morgan Sheng. 2018. “Microglia in Alzheimer’s Disease.”. The Journal of Cell Biology 217 (2): 459-72.
A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci.
Chang, Diana, Mike A Nalls, Ingileif B Hallgrímsdóttir, Julie Hunkapiller, Marcel van der Brug, Fang Cai, International Parkinson’s Disease Genomics Consortium, et al. 2017. “A Meta-Analysis of Genome-Wide Association Studies Identifies 17 New Parkinson’s Disease Risk Loci.”. Nature Genetics 49 (10): 1511-16.
Interfering with the Chronic Immune Response Rescues Chronic Degeneration After Traumatic Brain Injury.
Ertürk, Ali, Susanne Mentz, Erik E Stout, Maj Hedehus, Sara L Dominguez, Lisa Neumaier, Franziska Krammer, et al. 2016. “Interfering With the Chronic Immune Response Rescues Chronic Degeneration After Traumatic Brain Injury.”. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 36 (38): 9962-75.