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Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites.

Publication: Journal Article

McPhillie, Martin J, Ying Zhou, Mark R Hickman, James A Gordon, Christopher R Weber, Qigui Li, Patty J Lee, et al. 2020. “Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites.”. Frontiers in Cellular and Infection Microbiology 10: 203.

Corrigendum: Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication.

Publication: Journal Article

Lee, Ji-Hye, Beom Seok Park, Intekhab Alam, Kang R Han, Scott B Biering, Soo J Kim, Jayoung Choi, et al. 2019. “Corrigendum: Insight Into the Interaction Between RNA Polymerase and VPg for Murine Norovirus Replication.”. Frontiers in Microbiology 10: 32.

Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases.

Publication: Journal Article

Biering, Scott B, Jayoung Choi, Rachel A Halstrom, Hailey M Brown, Wandy L Beatty, Sanghyun Lee, Broc T McCune, et al. 2017. “Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases.”. Cell Host & Microbe 22 (1): 74-85.e7.

Clec16a is Critical for Autolysosome Function and Purkinje Cell Survival.

Publication: Journal Article

Redmann, Veronika, Christopher A Lamb, Seungmin Hwang, Robert C Orchard, Sungsu Kim, Minoo Razi, Ashley Milam, et al. 2016. “Clec16a Is Critical for Autolysosome Function and Purkinje Cell Survival.”. Scientific Reports 6: 23326.

Discovery of Potent STT3A/B Inhibitors and Assessment of Their Multipathogen Antiviral Potential and Safety.

Publication: Journal Article

Pero, Joseph E, Elizabeth A Mueller, Ashley M Adams, Ramona S Adolph, Parikshit Bagchi, Dale Balce, Marcus Bantscheff, et al. 2024. “Discovery of Potent STT3A/B Inhibitors and Assessment of Their Multipathogen Antiviral Potential and Safety.”. Journal of Medicinal Chemistry.

Autophagy regulates tumor growth and metastasis.

Publication: Journal Article

Qiang, Lei, Baozhong Zhao, Mei Ming, Ning Wang, Tong-Chuan He, Seungmin Hwang, Andrew Thorburn, and Yu-Ying He. 2023. “Autophagy Regulates Tumor Growth and Metastasis.”. BioRxiv.

Seungmin "Sam" Hwang

Person: Principal Investigator

Seungmin “Sam” Hwang is a senior translation group leader within the Center for Integrated Solutions for Infectious Diseases ( CISID) at the Broad Institute of MIT and Harvard. Hwang joined the Broad Institute in September 2023, and the focus of his research is to elucidate the mechanisms of organ...

Publications

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https://www.ncbi.nlm.nih.gov/myncbi/seungmin.hwang.1/bibliography/public/ 1. Park J, Seo T, Hwang S, Lee D, Gwack Y, Choe J. 2000. The K-bZIP protein from Kaposi's sarcoma-associated herpesvirus interacts with p53 and represses its transcriptional activity. J Virol 74:11977-82. 2. Lim C, Gwack Y...

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

Publication: Journal Article

Klionsky, Daniel J, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, et al. 2021. “Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th Edition)1.”. Autophagy 17 (1): 1-382.

Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.

Publication: Journal Article

Finethy, Ryan, Jacob Dockterman, Miriam Kutsch, Nichole Orench-Rivera, Graham D Wallace, Anthony S Piro, Sarah Luoma, et al. 2020. “Dynamin-Related Irgm Proteins Modulate LPS-Induced Caspase-11 Activation and Septic Shock.”. EMBO Reports 21 (11): e50830.