Mounica Vallurupalli
I am a physician-scientist interested in functional genomics, transcriptional regulation and myeloid disease biology.
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Transcriptional condensates in cancer
Tutorials
Workflow Turnaround
Disease Areas of Focus
Retinal Inherited retinal degenerations (IRDs) are characterized by progressive dysfunction and death of rod and cone photoreceptor cells, leading to vision loss, and are one of the most genetically diverse groups of inherited disorders. Identifying the genetic cause of patients’ IRD has become...
Cite Us
How to cite CellProfiler in publications (the project's survival depends on it!) CellProfiler for cells (feel free to cite the most recent) : Stirling DR, Swain-Bowden MJ, Lucas AM, Carpenter AE, Cimini BA, Goodman A (2021). CellProfiler 4: improvements in speed, utility and usability. BMC...
Community Enagagment
COBA’s mission is to catalyze the entire bioimage analysis software community. What have we accomplished thus far? Scientific Community Image Forum We created and sponsor the Scientific Community Image Forum. This forum has brought together dozens of open source image analysis platforms to one...
Software and code
DeepProfiler DeepProfiler is a set of tools that allow you to use deep learning for analyzing imaging data in high-throughput biological experiments. Documentation and instructions for DeepProfiler can be found in our Handbook and the code is located on the GitHub page. Cytominer The Pycytominer...
BRAF mutation predicts sensitivity to MEK inhibition
Solit, David, Levi Garraway, Christine Pratilas, Ayana Sawai, Gad Getz, Andrea Basso, Qing Ye, et al. 2006. “BRAF Mutation Predicts Sensitivity to MEK Inhibition”. Nature 439 (7074): 358-62.
Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia
Jaffe, Jacob, Yan Wang, Ho Man Chan, Jinghui Zhang, Robert Huether, Gregory Kryukov, Hyo-eun Bhang, et al. 2013. “Global Chromatin Profiling Reveals NSD2 Mutations in Pediatric Acute Lymphoblastic Leukemia”. Nat Genet 45 (11): 1386-91.