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Impaired microRNA processing enhances cellular transformation and tumorigenesis

Publication: Journal Article

Kumar, M. S., J. Lu, K. L. Mercer, T. R. Golub, and T. Jacks. 2007. “Impaired MicroRNA Processing Enhances Cellular Transformation and Tumorigenesis”. Nat Genet 39: 673-7.

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Publication: Journal Article

Lawrence, M. S., P. Stojanov, P. Polak, G. V. Kryukov, K. Cibulskis, A. Sivachenko, S. L. Carter, et al. 2013. “Mutational Heterogeneity in Cancer and the Search for New Cancer-Associated Genes”. Nature 499: 214-18.

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

Publication: Journal Article

Lechman, E. R., B. Gentner, S. W. K. Ng, E. M. Schoof, P. Galen, J. A. Kennedy, S. Nucera, et al. 2016. “MiR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells”. Cancer Cell 29: 602-6.

The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts

Publication: Journal Article

Lessnick, S. L., C. S. Dacwag, and T. R. Golub. 2002. “The Ewing’s Sarcoma Oncoprotein EWS/FLI Induces a P53-Dependent Growth Arrest in Primary Human Fibroblasts”. Cancer Cell 1: 393-401.

Data is released publicly! Find the data and details at our JUMP Cell Painting Datasets landing page on Github. If you'd like to take a look at the data interactively, Ardigen provides the free, public JUMP-CP Data Explorer to search for similarities between various phenotypes and the corresponding...

Broad Institute launches academic-industry cell imaging consortium to speed drug discovery and development

News: July 10, 2020

The Broad Institute of MIT and Harvard today announced that the Imaging Platform, together with industry and non-profit partners, has launched a new collaboration to create a massive cell-imaging dataset, displaying more than 1 billion cells responding to over 140,000 small molecules and genetic...

Directions To Install CellProfiler Analyst on Mac

Page

CellProfiler-Analyst requires a 64bit-Java 8 Java Development Kit (JDK), a special version of Java that allows CPA to open microscope images from many different vendors using the BioFormats library. You will need to install this software and configure your computer to run it properly. Step 0: Check...

Jen Q. Pan, Ph.D.

Person: Director, Translational Neurobiology, Institute Scientist,

Dr. Pan has more than 15 years of experience investigating the function, molecular genetics and pharmacology of ion channels. As the Director for Translational Neurobiology at Stanley Center, Dr. Pan aspires to translate the understanding of the genetics and biology of psychiatric and neurological...

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Impaired microRNA processing enhances cellular transformation and tumorigenesis

Mutational heterogeneity in cancer and the search for new cancer-associated genes

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts

Aditya Pratapa PhD

Eric Bueno

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Broad Institute launches academic-industry cell imaging consortium to speed drug discovery and development

Directions To Install CellProfiler Analyst on Mac

Jen Q. Pan, Ph.D.