Search

Search results

205 results found

News & Events

Page

October 31, 2025 Carl June, Bruce Levine, Isabelle Rivière, and Michel Sadelain receive the 2025 Merkin Prize at the Broad Institute for chimeric antigen receptor (CAR) T-cell therapy Produced by the Heritage Provider Network video team This groundbreaking form of personalized cancer immunotherapy...

Nominate

Page

Nominations for the 2026 Merkin Prize have closed. Nominations for the 2027 Prize open in August 2026. Join the Merkin Prize mailing list to receive updates and notifications. Join mailing list

CD300LF Polymorphisms of Inbred Mouse Strains Confer Resistance to Murine Norovirus Infection in a Cell Type-Dependent Manner.

Publication: Journal Article

Furlong, Kevin, Scott B Biering, Jayoung Choi, Craig B Wilen, Robert C Orchard, Christiane E Wobus, Christopher A Nelson, et al. 2020. “CD300LF Polymorphisms of Inbred Mouse Strains Confer Resistance to Murine Norovirus Infection in a Cell Type-Dependent Manner.”. Journal of Virology 94 (17).

Murine Norovirus Infection Induces TH1 Inflammatory Responses to Dietary Antigens.

Publication: Journal Article

Bouziat, Romain, Scott B Biering, Elaine Kouame, Kishan A Sangani, Soowon Kang, Jordan D Ernest, Mukund Varma, et al. 2018. “Murine Norovirus Infection Induces TH1 Inflammatory Responses to Dietary Antigens.”. Cell Host & Microbe 24 (5): 677-688.e5.

LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens.

Publication: Journal Article

Yokoyama, Christine C, Megan T Baldridge, Daisy W Leung, Guoyan Zhao, Chandni Desai, Ta-Chiang Liu, Vladimir E Diaz-Ochoa, et al. 2018. “LysMD3 Is a Type II Membrane Protein Without an in Vivo Role in the Response to a Range of Pathogens.”. The Journal of Biological Chemistry 293 (16): 6022-38.

Quo vadis? Interferon-inducible GTPases go to their target membranes via the LC3-conjugation system of autophagy.

Publication: Journal Article

Choi, Jayoung, Scott B Biering, and Seungmin Hwang. 2017. “Quo Vadis? Interferon-Inducible GTPases Go to Their Target Membranes via the LC3-Conjugation System of Autophagy.”. Small GTPases 8 (4): 199-207.

Targeting by AutophaGy proteins (TAG): Targeting of IFNG-inducible GTPases to membranes by the LC3 conjugation system of autophagy.

Publication: Journal Article

Park, Sungwoo, Jayoung Choi, Scott B Biering, Erin Dominici, Lelia E Williams, and Seungmin Hwang. 2016. “Targeting by AutophaGy Proteins (TAG): Targeting of IFNG-Inducible GTPases to Membranes by the LC3 Conjugation System of Autophagy.”. Autophagy 12 (7): 1153-67.

Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication.

Publication: Journal Article

Tarakanova, Vera L, Van Leung-Pineda, Seungmin Hwang, Chiao-Wen Yang, Katie Matatall, Mickael Basson, Ren Sun, Helen Piwnica-Worms, Barry P Sleckman, and Herbert W Virgin. 2007. “Gamma-Herpesvirus Kinase Actively Initiates a DNA Damage Response by Inducing Phosphorylation of H2AX to Foster Viral Replication.”. Cell Host & Microbe 1 (4): 275-86.

The K-bZIP protein from Kaposi's sarcoma-associated herpesvirus interacts with p53 and represses its transcriptional activity.

Publication: Journal Article

Park, J, T Seo, S Hwang, D Lee, Y Gwack, and J Choe. 2000. “The K-BZIP Protein from Kaposi’s Sarcoma-Associated Herpesvirus Interacts With P53 and Represses Its Transcriptional Activity.”. Journal of Virology 74 (24): 11977-82.

Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle.

Publication: Journal Article

Starr, Tregei, Robert Child, Tara D Wehrly, Bryan Hansen, Seungmin Hwang, Carlos López-Otín, Herbert W Virgin, and Jean Celli. 2012. “Selective Subversion of Autophagy Complexes Facilitates Completion of the Brucella Intracellular Cycle.”. Cell Host & Microbe 11 (1): 33-45.