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Daniel Ardeljan
Todd Golub
Todd Golub is director of the Broad Institute of MIT and Harvard, and a founding core member of the institute. He is also a member of the faculty of the Dana-Farber Cancer Institute and Harvard Medical School. Golub is a world-renowned physician-scientist who pioneered the application of genomics to...
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Assistant to the Director Caitlin Ingelfinger +1 (617) 714-7350 trgoffice@broadinstitute.org Assistant to the Director Lee O'Neil trgoffice@broadinstitute.org Senior Laboratory Manager Maria Cecilia Saberi msaberi@broadinstitute.org Inquiries regarding open positions: TRGapplications@broadinstitute...
An intravenous DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies
Tabrizi, Shervin, Carmen Martin-Alonso, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Zhenyi An, Sahil Patel, et al. 2023. “An Intravenous DNA-Binding Priming Agent Protects Cell-Free DNA and Improves the Sensitivity of Liquid Biopsies”. https://doi.org/10.1101/2023.01.13.523947.
Circulating tumor DNA association with residual cancer burden after neoadjuvant chemotherapy in triple-negative breast cancer in TBCRC 030
Parsons, Heather A., Timothy Blewett, Xiangying Chu, Sainetra Sridhar, Katheryn Santos, Kan Xiong, Vandana G. Abramson, et al. 2023. “Circulating Tumor DNA Association With Residual Cancer Burden After Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer in TBCRC 030”. MedRxiv.
DNA-based copy number analysis confirms genomic evolution of PDX models
Hoge, Anna C H, , Anat Zimmer, Minjeong Ko, Linoy Raz, Rameen Beroukhim, Todd R Golub, Gavin Ha, and Uri Ben David. 2022. “DNA-Based Copy Number Analysis Confirms Genomic Evolution of PDX Models”. NPJ Precis Oncol 6 (1): 30.
Dean Procter
A metastasis map of human cancer cell lines
Jin, X., Z. Demere, K. Nair, A. Ali, G. B. Ferraro, T. Natoli, A. Deik, et al. 2020. “A Metastasis Map of Human Cancer Cell Lines”. Nature 588: 331-36.
UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia
Kitareewan, S., I. Pitha-Rowe, D. Sekula, C. H. Lowrey, M. J. Nemeth, T. R. Golub, S. J. Freemantle, and E. Dmitrovsky. 2002. “UBE1L Is a Retinoid Target That Triggers PML/RARalpha Degradation and Apoptosis in Acute Promyelocytic Leukemia”. Proc Natl Acad Sci U S A 99: 3806-11.