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Accession number BBBC048 · Version 1 Example images Biological application Abstract: We show that deep convolutional neural networks combined with nonlinear dimension reduction enable reconstructing biological processes based on raw image data. We demonstrate this by reconstructing the cell cycle of...

Identification and segmentation Accession Description Mode Fields per Sample Total Fields Total Images Ground Truth BBBC001 Human HT29 colon-cancer cells Fluorescent 6 6 6 BBBC002 Drosophila Kc167 cells Fluorescent 5 50 50 BBBC003 Mouse embryos DIC 15 15 15 BBBC004 Synthetic cells Fluorescent 20 100...

Accession number BBBC005 · Version 1 Example images In focus Out of focus True foreground Biological application Since robust foreground/background separation and segmentation of cellular objects (i.e.,identification of which pixels below to which objects) strongly depends on image quality, focus...

Accession number BBBC007 · Version 1 Example images DNA Actin Outlined nuclei Outlined cells Biological application Drosophila melanogaster Kc167 cells were stained for DNA (to label nuclei) and actin (a cytoskeletal protein, to show the cell body). Automatic cytometry requires that cells be...

Accession number BBBC039 · Version 1 Example images Description of the biological application This image set is part of a high-throughput chemical screen on U2OS cells, with examples of 200 bioactive compounds. The effect of the treatments was originally imaged using the Cell Painting assay...

Accession number BBBC012 · Version 1 Example images Positive: pmk-1(km25) Negative: wild type Biological application This selection of images show transgenic C. elegans expressing the promoter of gene clec-60 fused to GFP. The clec-60 gene is up-regulated during S. aureus infection [Irazoqui et al...