Defining a Cancer Dependency Map
Tsherniak, A., F. Vazquez, P. G. Montgomery, B. A. Weir, G. Kryukov, G. S. Cowley, S. Gill, et al. 2017. “Defining a Cancer Dependency Map”. Cell 170: 564-576 e16.
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Mitochondrial metabolism promotes adaptation to proteotoxic stress
Tsvetkov, P., A. Detappe, K. Cai, H. R. Keys, Z. Brune, W. Ying, P. Thiru, et al. 2019. “Mitochondrial Metabolism Promotes Adaptation to Proteotoxic Stress”. Nat Chem Biol 15: 681-89.
Growth and characterization of epithelial cells from normal human uterine ectocervix and endocervix
Turyk, M. E., T. R. Golub, N. B. Wood, J. L. Hawkins, and G. D. Wilbanks. 1989. “Growth and Characterization of Epithelial Cells from Normal Human Uterine Ectocervix and Endocervix”. In Vitro Cell Dev Biol 25: 544-56.
microRNA expression during trophectoderm specification
Viswanathan, S. R., C. H. Mermel, J. Lu, C. W. Lu, T. R. Golub, and G. Q. Daley. 2009. “MicroRNA Expression During Trophectoderm Specification”. PLoS One 4: e6143.
Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease
Wang, J., H. Iwasaki, A. Krivtsov, P. G. Febbo, A. R. Thorner, P. Ernst, E. Anastasiadou, et al. 2005. “Conditional MLL-CBP Targets GMP and Models Therapy-Related Myeloproliferative Disease”. EMBO J 24: 368-81.
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
Xie, X., J. Lu, E. J. Kulbokas, T. R. Golub, V. Mootha, K. Lindblad-Toh, E. S. Lander, and M. Kellis. 2005. “Systematic Discovery of Regulatory Motifs in Human Promoters and 3’ UTRs by Comparison of Several Mammals”. Nature 434: 338-45.
HiC-bench: Comprehensive and Reproducible Hi-C data Analysis Designed for Parameter Exploration and Benchmarking
Lazaris, Charalampos, Stephen Kelly, Panagiotis Ntziachristos, Iannis Aifantis, and Aristotelis Tsirigos. 2017. “HiC-Bench: Comprehensive and Reproducible Hi-C Data Analysis Designed for Parameter Exploration and Benchmarking”. BMC Genomics 18: 22-22.
The landscape of somatic copy-number alteration across human cancers
Beroukhim, R., C. H. Mermel, D. Porter, G. Wei, S. Raychaudhuri, J. Donovan, J. Barretina, et al. 2010. “The Landscape of Somatic Copy-Number Alteration across Human Cancers”. Nature 463: 899-905.
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks
Butte, A. J., P. Tamayo, D. Slonim, T. R. Golub, and I. S. Kohane. 2000. “Discovering Functional Relationships Between RNA Expression and Chemotherapeutic Susceptibility Using Relevance Networks”. Proc Natl Acad Sci U S A 97: 12182-6.
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes
Chapuy, B., C. Stewart, A. J. Dunford, J. Kim, A. Kamburov, R. A. Redd, M. S. Lawrence, et al. 2018. “Molecular Subtypes of Diffuse Large B Cell Lymphoma Are Associated With Distinct Pathogenic Mechanisms and Outcomes”. Nat Med 24: 679-90.