Search

Search results

607 results found

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles

Publication: Journal Article

Subramanian, A., R. Narayan, S. M. Corsello, D. D. Peck, T. E. Natoli, X. Lu, J. Gould, et al. 2017. “A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles”. Cell 171: 1437-1452 e17.

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma

Publication: Journal Article

Tirosh, I., A. S. Venteicher, C. Hebert, L. E. Escalante, A. P. Patel, K. Yizhak, J. M. Fisher, et al. 2016. “Single-Cell RNA-Seq Supports a Developmental Hierarchy in Human Oligodendroglioma”. Nature 539: 309-13.

Lin28 promotes transformation and is associated with advanced human malignancies

Publication: Journal Article

Viswanathan, S. R., J. T. Powers, W. Einhorn, Y. Hoshida, T. L. Ng, S. Toffanin, M. O’Sullivan, et al. 2009. “Lin28 Promotes Transformation and Is Associated With Advanced Human Malignancies”. Nat Genet 41: 843-8.

Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling

Publication: Journal Article

Wawer, M. J., K. Li, S. M. Gustafsdottir, V. Ljosa, N. E. Bodycombe, M. A. Marton, K. L. Sokolnicki, et al. 2014. “Toward Performance-Diverse Small-Molecule Libraries for Cell-Based Phenotypic Screening Using Multiplexed High-Dimensional Profiling”. Proc Natl Acad Sci U S A 111: 10911-6.

Three-dimensional Chromatin Landscapes in T cell Acute Lymphoblastic Leukemia

Publication: Journal Article

Kloetgen, Andreas, Palaniraja Thandapani, Panagiotis Ntziachristos, Yohana Ghebrechristos, Sofia Nomikou, Charalampos Lazaris, Xufeng Chen, et al. 2020. “Three-Dimensional Chromatin Landscapes in T Cell Acute Lymphoblastic Leukemia”. Nat Genet 52: 388-400.

cmg

Human U2OS Cells – profiling bioactive compounds using Cell Painting

Page

Accession number BBBC036 · Version 1 Example images Description of the biological application Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each sample so that similarities between profiles reflect similarities between samples. This...

Training

Page

Impact on Human Health

Page

Our CellProfiler software has yielded discoveries in several translational projects, some of which have had a direct impact on the treatment of disease. For example, CellProfiler has been used to identify several small molecules that are effective in treating particular diseases in mouse models. In...

Contact

Page