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Our Team

The Sheng lab is committed to diversity, equity and inclusion and our lab is dedicated to ensuring a welcoming and safe space for all individuals. We actively work to increase the breadth of our applicant pools to create an environment that supports and retains a richly diverse community...

Merkin Prize Jury

The Merkin Prize Jury is composed of scientific leaders from academia and industry in the US and Europe.

Nominate

Nominations for the 2026 Merkin Prize are now open. Click the ”nominate” button below to submit a nomination. Deadline: Friday, December 5, 2025 at 11:59 p.m. ET. Nominate Nomination Package Requirements Contact information for nominator Nominees’ names and organizations If available, please share...

Published pipelines

CellProfiler enables reproducible research because a saved pipeline includes all the modules and settings. Here, we provide links to pipelines used in some published studies, as well as the version of CellProfiler used to create them. You can instead download the most current version of CellProfiler...

2025 Merkin Prize in Biomedical Technology Recipients

Carl June University of Pennsylvania Perelman School of Medicine Carl June is the Richard W. Vague professor in immunotherapy at the Perelman School of Medicine at the University of Pennsylvania, where he is also the director of the Center for Cellular Immunotherapies. In addition, he is the...

News & Events

May 21, 2025 2025 Merkin Prize in Biomedical Technology awarded to Carl June, Bruce Levine, Isabelle Rivière, and Michel Sadelain for development of CAR T-cell Therapy Produced by the Broad Institute of MIT and Harvard Four biomedical innovators have been jointly awarded the 2025 Richard N. Merkin...

Contribute to the BBBC

We welcome contributions of the following: Image sets with descriptions and ground truth High-throughput image sets Published benchmarking results of algorithms applied to the BBBC image sets Corrections to existing descriptions or ground truth Feedback on the benchmarking methodology or other...

Introduction

CellProfiler Analyst (CPA) provides tools for classifying biological images and exploring and visualizing multidimensional data (particularly from high-throughput experiments) that has been extracted from companion image analysis software CellProfiler. CellProfiler Analyst’s primary tools: Image...

Human HT29 colon-cancer cells

Accession number BBBC008 · Version 1 Example images Biological application These images are of human HT29 colon cancer cells, a cell line that has been widely used for the study of many normal and neoplastic processes. A set of about 43,000 such images was used by Moffat et al. (Cell, 2006) to...