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Accession number BBBC032 · Version 1 Example images Description of the biological application Segmenting nuclei in 3D images can be challenging especially when nuclei are clustered not only in XY plane but also in XZ and YZ planes. Manually annotated ground truth provides a reference for image...

Accession number BBBC034 · Version 1 Example images Description of the biological application Segmenting nuclei in 3D images can be challenging especially when nuclei are clustered and have different intensity. This image set contains a clustered monolayer of nuclei that can be difficult to segment...

Accession number BBBC031 · Version 1 Example images Description of the biological application We generated a synthetic HCS dataset simulating drugs perturbing the cell shape and the expressions of proteins (here represented by different colours). The dataset is useful for testing classification and...

Accession number BBBC040 · Version 1 Example images Biological application An ideal small-molecule screening library would be enriched in non-redundant bioactive compounds that maximize the performance diversity of the library. The construction of such libraries would be aided by a rapid feedback...

COBA’s mission is to catalyze the entire bioimage analysis software community. What have we accomplished thus far? Scientific Community Image Forum We created and sponsor the Scientific Community Image Forum. This forum has brought together dozens of open source image analysis platforms to one...

Accession number BBBC050 · Version 2 Example images Biological application Cell dynamics during the early mouse embryogenesis change spatiotemporally. For understanding the mechanism of this developmental process, imaging cell dynamics by live-cell imaging of fluorescently labeled nuclei and...

KIDNEY DISEASE Autosomal dominant MUC1 kidney disease (MKD, also known as ADTKD-MUC1, and formerly called MCKD1) is a rare hereditary renal disease that ultimately requires dialysis or kidney transplantation for patients. For decades, scientists had known the genetic “neighborhood” of the mutation...

The groundbreaking, scalable technology is widely used in laboratories around the world today to efficiently produce large amounts of protein and RNA.

CellProfiler and CellProfiler Analyst Our lab previously launched and led the CellProfiler and CellProfiler Analyst projects, beloved by biologists around the world for bioimage analysis and cited over 15,000 times. They are now developed and maintained by the Cimini lab (since 2021). DeepProfiler ​...

F. William Studier was born in 1936 in Waverly, Iowa and went to Yale (BS, Biophysics, 1958), Caltech (PhD, Biophysics, 1963), and Stanford University for postdoctoral research in biochemistry. In 1964 he joined the biology department in Brookhaven National Laboratory, which he chaired from 1990...