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Massively parallel enrichment of low-frequency alleles enables duplex sequencing at low depth

Publication: Journal Article

Gydush, Gregory, Erica Nguyen, Jin H Bae, Timothy Blewett, Justin Rhoades, Sarah C Reed, Douglas Shea, et al. 2022. “Massively Parallel Enrichment of Low-Frequency Alleles Enables Duplex Sequencing at Low Depth”. Nat Biomed Eng 6 (3): 257-66.

Publisher Correction: DNA-based copy number analysisconfirms genomic evolution of PDX models.

Publication: Journal Article

Hoge, Anna C H, Michal Getz, Anat Zimmer, Minjeong Ko, Linoy Raz, Rameen Beroukhim, Todd R. Golub, Gavin Ha, and Uri Ben-David. 2022. “Publisher Correction: DNA-Based Copy Number Analysisconfirms Genomic Evolution of PDX Models.”. NPJ Precis Oncol 6 (50).

Copper induces cell death by targeting lipoylated TCA cycle proteins

Publication: Journal

Tsvetkov, Peter, Shannon Coy, Boryana Petrova, Margaret Dreishpoon, Ana Verma, Mai Abdusamad, Jordan Rossen, et al. 2022. “Copper Induces Cell Death by Targeting Lipoylated TCA Cycle Proteins”. https://doi.org/10.1126/science.abf0529.

FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS

Publication: Journal Article

Ferraro, Gino B, Ahmed Ali, Alba Luengo, David P Kodack, Amy Deik, Keene L Abbott, Divya Bezwada, et al. 2021. “FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS”. Nat Cancer 2 (4): 414-28.

FDX1 regulates cellular protein lipoylation through direct binding to LIAS

Publication: Journal Article

Dreishpoon, Margaret B, Nolan R Bick, Boryana Petrova, Douglas M Warui, Alison Cameron, Squire J Booker, Naama Kanarek, Todd R Golub, and Peter Tsvetkov. 2023. “FDX1 Regulates Cellular Protein Lipoylation through Direct Binding to LIAS”. J Biol Chem 299 (9).

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Map shows how cancer cells spread through the body Broad@15 Talk Series; The March Toward Cancer Precision Medicine 09/2019

Heejo Choi

Person: Computational Biologist

I am a computational biologist interested in the integration, interpretation, and visualization of data elucidating cancer dependencies in the context of the tumor microenvironment.

Andrea Clocchiatti

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I am a research scientist interested in identifying cancer vulnerabilities in vivo linked to the complex ecosystem of cancer microenvironment.

Narsis Attar

Person: Postdoctoral Fellow