Mei-Hua Hall, Ph.D. Person: Director, Psychosis Neurobiology Laboratory, McLean Hospital, Associate Professor of Psychiatry, Harvard Medical School
Peter Tsvetkov Person: Associate Member Broad Institute of MIT and Harvard; Principal Investigator BIDMC
A metastasis map of human cancer cell lines Publication: Journal Article Jin, X., Z. Demere, K. Nair, A. Ali, G. B. Ferraro, T. Natoli, A. Deik, et al. 2020. “A Metastasis Map of Human Cancer Cell Lines”. Nature 588: 331-36.
UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia Publication: Journal Article Kitareewan, S., I. Pitha-Rowe, D. Sekula, C. H. Lowrey, M. J. Nemeth, T. R. Golub, S. J. Freemantle, and E. Dmitrovsky. 2002. “UBE1L Is a Retinoid Target That Triggers PML/RARalpha Degradation and Apoptosis in Acute Promyelocytic Leukemia”. Proc Natl Acad Sci U S A 99: 3806-11.
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9 Publication: Journal Article Krivtsov, A. V., D. Twomey, Z. Feng, M. C. Stubbs, Y. Wang, J. Faber, J. E. Levine, et al. 2006. “Transformation from Committed Progenitor to Leukaemia Stem Cell Initiated by MLL-AF9”. Nature 442: 818-22.
MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells Publication: Journal Article Kryukov, G. V., F. H. Wilson, J. R. Ruth, J. Paulk, A. Tsherniak, S. E. Marlow, F. Vazquez, et al. 2016. “MTAP Deletion Confers Enhanced Dependency on the PRMT5 Arginine Methyltransferase in Cancer Cells”. Science 351: 1214-8.
A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers Publication: Journal Article Lee, R. S., C. Stewart, S. L. Carter, L. Ambrogio, K. Cibulskis, C. Sougnez, M. S. Lawrence, et al. 2012. “A Remarkably Simple Genome Underlies Highly Malignant Pediatric Rhabdoid Cancers”. J Clin Invest 122: 2983-8.