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Human MCF7 cells – compound-profiling experiment

Accession number BBBC021 · Version 1 Example Images Actin disrupter Aurora kinase inhbitor Eg5 inhibitor Tubulin destabilizer Tubulin stabilizer Description of the biological application Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each...

Human U2OS cells – Gene overexpression profiling experiment

Accession number BBBC037 · Version 1 Example images Description of the biological application The image set can be used to functionally annotate the genes through comparing their overexpression morphological profiles. Images Images from five fluorescent channels were captured at 20x magnification on...

C. elegans metabolism assay

Accession number BBBC011 · Version 1 Example images Negative control: wild type Positive control: fat Biological application Images are controls from an RNA interference screen for genes affecting fat mass in the nematode C.elegans. The animals are stained with oil red O, a non-flourescentdye which...

Human U2OS cells cytoplasm–nucleus translocation

Accession number BBBC013 · Version 1 Example images Positive Negative Biological application This 96-well plate has images of cytoplasm to nucleus translocation of the Forkhead (FKHR-EGFP) fusion protein in stably transfected human osteosarcoma cells, U2OS. In proliferating cells, FKHR is localized...

Human U2OS cells transfluor

Accession number BBBC015 · Version 1 Example images Positive Negative Biological application The images are of a human osteosarcoma cell line (U2OS) co-expressing beta2 (b2AR) adrenergic receptor and arrestin-GFP protein molecules. The receptor was modified-type that generates "vesicle-type" spots...

Human U2OS cells transfluor

Accession number BBBC016 · Version 1 Example images Positive Negative Description of the biological application This image set is of a Transfluor assay where an orphan GPCR is stably integrated into the b-arrestin GFP expressing U2OS cell line. After one hour incubation with a compound the cells...

Kaggle 2018 Data Science Bowl

Accession number BBBC038 · Version 1 Example images Description of the biological application This image data set contains a large number of segmented nuclei images and was created for the Kaggle 2018 Data Science Bowl sponsored by Booz Allen Hamilton with cash prizes. The image set was a testing...

P. vivax (malaria) infected human blood smears

Accession number BBBC041· Version 1 Example images Description of the biological application Malaria is a disease caused by Plasmodium parasites that remains a major threat in global health, affecting 200 million people and causing 400,000 deaths a year. The main species of malaria that affect...

Rat astrocyte cells

Accession number BBBC042 · Version 1 Example images Description of the biological application The morphology of astrocytes is highly heterogeneous and counting them is currently a laborious task. Development of fully automated counting methods for astrocytes from immunohistological images without...

Mouse hippocampal presynaptic terminals (vGlut-1 and vGat)

Accession number BBBC044 · Version 1 Example images Description of the biological application These images are of mouse hippocampal presynaptic terminals and the goal is to extract presynaptic terminals' densities. The presented seet of images were being used to validate the accuracy of automatic...