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Valeria Padovano
Senior Scientist
Dara Manoach, Ph.D.
Anna awarded ASN Young Investigator Award!
Read more about the Donald W. Seldin Young Investigator Award here.
Vignesh Shanmugam
I am a hematopathologist with interests in applying single cell and tissue imaging technologies to better understand the biology of lymphoid malignancies and develop new diagnostic approaches.
Mounica Vallurupalli
I am a physician-scientist interested in functional genomics, transcriptional regulation and myeloid disease biology.
Genomic evolution of cancer models: perils and opportunities
Ben-David, U., R. Beroukhim, and T. R. Golub. 2019. “Genomic Evolution of Cancer Models: Perils and Opportunities”. Nat Rev Cancer 19: 97-109.
A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay
Bray, M. A., S. M. Gustafsdottir, M. H. Rohban, S. Singh, V. Ljosa, K. L. Sokolnicki, J. A. Bittker, et al. 2017. “A Dataset of Images and Morphological Profiles of 30 000 Small-Molecule Treatments Using the Cell Painting Assay”. Gigascience 6: 1-5.
WRN helicase is a synthetic lethal target in microsatellite unstable cancers
Chan, E. M., T. Shibue, J. M. McFarland, B. Gaeta, M. Ghandi, N. Dumont, A. Gonzalez, et al. 2019. “WRN Helicase Is a Synthetic Lethal Target in Microsatellite Unstable Cancers”. Nature 568: 551-56.
CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2
Chen, L., G. Alexe, N. V. Dharia, L. Ross, A. B. Iniguez, A. S. Conway, E. J. Wang, et al. 2018. “CRISPR-Cas9 Screen Reveals a MYCN-Amplified Neuroblastoma Dependency on EZH2”. J Clin Invest 128: 446-62.