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Paolo is a machine learning engineer working on cardiovascular disease prediction and genetic discovery via deep learning. Paolo holds a PhD (from Yale University) and a MS (from University of Pisa, Italy), both in Biomedical Engineering. His areas of expertise include computer vision...

Caveolae in CNS arterioles mediate neurovascular coupling.

Publication: Journal Article

Chow, Brian W, Vicente Nuñez, Luke Kaplan, Adam J Granger, Karina Bistrong, Hannah L Zucker, Payal Kumar, Bernardo L Sabatini, and Chenghua Gu. 2020. “Caveolae in CNS Arterioles Mediate Neurovascular Coupling.”. Nature 579 (7797): 106-10.

The LGI1-ADAM22 protein complex directs synapse maturation through regulation of PSD-95 function.

Publication: Journal Article

Lovero, Kathryn L, Yuko Fukata, Adam J Granger, Masaki Fukata, and Roger A Nicoll. 2015. “The LGI1-ADAM22 Protein Complex Directs Synapse Maturation through Regulation of PSD-95 Function.”. Proceedings of the National Academy of Sciences of the United States of America 112 (30): E4129-37.

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Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner.

Publication: Journal Article

Granger, Adam J, Wengang Wang, Keiramarie Robertson, Mahmoud El-Rifai, Andrea F Zanello, Karina Bistrong, Arpiar Saunders, et al. 2020. “Cortical ChAT+ Neurons Co-Transmit Acetylcholine and GABA in a Target- and Brain-Region-Specific Manner.”. ELife 9.

Multi-transmitter neurons in the mammalian central nervous system.

Publication: Journal Article

Granger, Adam J, Michael L Wallace, and Bernardo L Sabatini. 2017. “Multi-Transmitter Neurons in the Mammalian Central Nervous System.”. Current Opinion in Neurobiology 45: 85-91.

Mechanisms and functions of GABA co-release.

Publication: Journal Article

Tritsch, Nicolas X, Adam J Granger, and Bernardo L Sabatini. 2016. “Mechanisms and Functions of GABA Co-Release.”. Nature Reviews. Neuroscience 17 (3): 139-45.

Cotransmission of acetylcholine and GABA.

Publication: Journal Article

Granger, Adam J, Nicole Mulder, Arpiar Saunders, and Bernardo L Sabatini. 2016. “Cotransmission of Acetylcholine and GABA.”. Neuropharmacology 100: 40-6.

How to Normalize Cell Painting Data

Blog: March 22, 2022

Rebecca Senft Workflow update June 2024 update Our recommended normalization workflow is evolving. Please see https://github.com/broadinstitute/jump-profiling-recipe/ for our latest developments on the normalization strategy in specific and aprofiling workflow in general. How to Normalize Cell...

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Paolo Di Achille

Caveolae in CNS arterioles mediate neurovascular coupling.

The LGI1-ADAM22 protein complex directs synapse maturation through regulation of PSD-95 function.

Publications

Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner.

Multi-transmitter neurons in the mammalian central nervous system.

Mechanisms and functions of GABA co-release.

Cotransmission of acetylcholine and GABA.

How to Normalize Cell Painting Data