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Liquid biopsy detection of genomic alterations in pediatric brain tumors from cell-free DNA in peripheral blood, CSF, and urine

Publication: Journal Article

Pagès, Mélanie, Denisse Rotem, Gregory Gydush, Sarah Reed, Justin Rhoades, Gavin Ha, Christopher Lo, et al. 2022. “Liquid Biopsy Detection of Genomic Alterations in Pediatric Brain Tumors from Cell-Free DNA in Peripheral Blood, CSF, and Urine”. Neuro Oncol.

Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner.

Publication: Journal Article

Granger, Adam J, Wengang Wang, Keiramarie Robertson, Mahmoud El-Rifai, Andrea F Zanello, Karina Bistrong, Arpiar Saunders, et al. 2020. “Cortical ChAT+ Neurons Co-Transmit Acetylcholine and GABA in a Target- and Brain-Region-Specific Manner.”. ELife 9.

Multi-transmitter neurons in the mammalian central nervous system.

Publication: Journal Article

Granger, Adam J, Michael L Wallace, and Bernardo L Sabatini. 2017. “Multi-Transmitter Neurons in the Mammalian Central Nervous System.”. Current Opinion in Neurobiology 45: 85-91.

Mechanisms and functions of GABA co-release.

Publication: Journal Article

Tritsch, Nicolas X, Adam J Granger, and Bernardo L Sabatini. 2016. “Mechanisms and Functions of GABA Co-Release.”. Nature Reviews. Neuroscience 17 (3): 139-45.

Cotransmission of acetylcholine and GABA.

Publication: Journal Article

Granger, Adam J, Nicole Mulder, Arpiar Saunders, and Bernardo L Sabatini. 2016. “Cotransmission of Acetylcholine and GABA.”. Neuropharmacology 100: 40-6.

Copper induces cell death by targeting lipoylated TCA cycle proteins

Publication: Journal Article

Tsvetkov, Peter, Shannon Coy, Boryana Petrova, Margaret Dreishpoon, Ana Verma, Mai Abdusamad, Jordan Rossen, et al. 2022. “Copper Induces Cell Death by Targeting Lipoylated TCA Cycle Proteins”. Science 375 (6586): 1254-61.

Customizing a Model for Fiber Segmentation, Part 3: Constructing a CellProfiler Pipeline

Blog: August 05, 2022

Melissa Gillis In the previous two sections of this blogpost I explained how I analyzed multiple methods to segment fluorescent images of collagen IV fibers, and generated accurate segmentation using an ilastik machine learning model. In this section I will explain how I constructed a CellProfiler...

Customizing a Model for Fiber Segmentation, Part 4: Analyzing the Results

Blog: August 05, 2022

Melissa Gillis In the final section of this blogpost series, I will discuss some of the benefits and drawbacks of this model and discuss some of the data I acquired from the images. This model was able to successfully segment the images that were not able to be accurately segmented by Pearl’s...

I2K 2022 Conference - From Images to Knowledge with ImageJ & Friends

News: January 03, 2022

The Center for Open Bioimage Analysis (COBA) at Broad Institute and LOCI UW-Madison, as well as the Fiji development team at Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, is pleased to formally announce the 2022 “From Images to Knowledge with ImageJ & Friends (I2K)”...

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