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JUMP Cell Painting protocol (v3) in press

News: December 01, 2022

The newly optimized version 3 of the protocol has been accepted! It is in press at Nature Protocols as Cimini et al. 2023.

Two publicly available portals to explore the data

News: March 28, 2023

Ardigen’s phenAID portal The phenAID JUMP-CP Explorer was created by the Ardigen Data Science and Software Development team to enable easy access and visualization of JUMP-CP data. The web-based application shows a phenotypic and structural representation of the data set colored by clusters. Users...

Data release & Manuscript in BioRxiv

News: March 28, 2023

We are excited to share that the JUMP Cell Painting Datasets now include most data components from all but one of the sources for the principal dataset (cpg0016), covering 116,000 chemical and over 20,000 genetic perturbations (covering ~15,000 genes). The first draft of metadata files are available...

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Blog: April 18, 2023

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Blog: April 18, 2023

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Thouis 'Ray' Jones, Sc.D.

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Principal Investigator, Novo Nordisk Foundation Center, Broad Institute

Activity-induced Polo-like kinase 2 is required for homeostatic plasticity of hippocampal neurons during epileptiform activity.

Publication: Journal Article

Seeburg, Daniel P, and Morgan Sheng. 2008. “Activity-Induced Polo-Like Kinase 2 Is Required for Homeostatic Plasticity of Hippocampal Neurons During Epileptiform Activity.”. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 28 (26): 6583-91.

Midrange affinity fluorescent Zn(II) sensors of the Zinpyr family: syntheses, characterization, and biological imaging applications.

Publication: Journal Article

Nolan, Elizabeth M, Jacek Jaworski, Maryann E Racine, Morgan Sheng, and Stephen J Lippard. 2006. “Midrange Affinity Fluorescent Zn(II) Sensors of the Zinpyr Family: Syntheses, Characterization, and Biological Imaging Applications.”. Inorganic Chemistry 45 (24): 9748-57.