Brady Walker
Project Coordinator, GRO and dGTEx
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Inaugural Merkin Prize in Biomedical Technology awarded to Dr. Marvin Caruthers for developing technology that efficiently synthesizes DNA
CONTACT Sarah Farris sarah@comsint.com VIDEO Link The $400,000 award recognizes the far-reaching medical impact of Dr. Caruthers’ development, in the early 1980s, of an efficient and fast method to synthesize nucleic acids. Cambridge, MA (June 28, 2023)—Dr. Marvin H. Caruthers of the University of...
Functional inference of gene regulation using single-cell multi-omics.
Kartha, Vinay K, Fabiana M Duarte, Yan Hu, Sai Ma, Jennifer G Chew, Caleb A Lareau, Andrew Earl, et al. 2022. “Functional Inference of Gene Regulation Using Single-Cell Multi-Omics.”. Cell Genomics 2 (9).
Drug addiction unveils a repressive methylation ceiling in EZH2-mutant lymphoma.
Kwok, Hui Si, Allyson M Freedy, Allison P Siegenfeld, Julia W Morriss, Amanda L Waterbury, Stephen M Kissler, and Brian B Liau. 2023. “Drug Addiction Unveils a Repressive Methylation Ceiling in EZH2-Mutant Lymphoma.”. Nature Chemical Biology.
Epigenetic clocks, aging, and cancer.
Johnstone, Sarah E, Vadim N Gladyshev, Martin J Aryee, and Bradley E Bernstein. 2022. “Epigenetic Clocks, Aging, and Cancer.”. Science (New York, N.Y.) 378 (6626): 1276-77.
Spatial genomics enables multi-modal study of clonal heterogeneity in tissues.
Zhao, Tongtong, Zachary D Chiang, Julia W Morriss, Lindsay M LaFave, Evan M Murray, Isabella Del Priore, Kevin Meli, et al. 2022. “Spatial Genomics Enables Multi-Modal Study of Clonal Heterogeneity in Tissues.”. Nature 601 (7891): 85-91.
Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging.
Gabriele, Michele, Hugo B Brandão, Simon Grosse-Holz, Asmita Jha, Gina M Dailey, Claudia Cattoglio, Tsung-Han S Hsieh, Leonid Mirny, Christoph Zechner, and Anders S Hansen. 2022. “Dynamics of CTCF- and Cohesin-Mediated Chromatin Looping Revealed by Live-Cell Imaging.”. Science (New York, N.Y.) 376 (6592): 496-501.
Abhishek Choudhary
Computational Scientist I, GRO and dGTEx
Bo Xia, Ph.D.
GRO Fellow & Junior Fellow at Harvard University
Omar Abudayyeh, Ph.D.
McGovern Fellow, Massachusetts Institute of Technology