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Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal
Krill‑Burger, Michael, Joshua M. Dempster, Ashir A. Borah, Brenton R. Paolella, David E. Root, Todd R. Golub, Jesse S. Boehm, et al. 2023. “Partial Gene Suppression Improves Identification of Cancer Vulnerabilities When CRISPR-Cas9 Knockout Is Pan-Lethal”. Genome Biol 24 (1).
Saoirse Hanbury
Single duplex DNA sequencing with CODEC detects mutations with high sensitivity
Bae, Jin H., Ruolin Liu, Eugenia Roberts, Erica Nguyen, Shervin Tabrizi, Justin Rhoades, Timothy Blewett, et al. 2023. “Single Duplex DNA Sequencing With CODEC Detects Mutations With High Sensitivity”. Nat Genet.
FDX1 regulates cellular protein lipoylation through direct binding to LIAS
Dreishpoon, Margaret B, Nolan R Bick, Boryana Petrova, Douglas M Warui, Alison Cameron, Squire J Booker, Naama Kanarek, Todd R Golub, and Peter Tsvetkov. 2023. “FDX1 Regulates Cellular Protein Lipoylation through Direct Binding to LIAS”. J Biol Chem 299 (9).
Heejo Choi
I am a computational biologist interested in the integration, interpretation, and visualization of data elucidating cancer dependencies in the context of the tumor microenvironment.
Andrea Clocchiatti
I am a research scientist interested in identifying cancer vulnerabilities in vivo linked to the complex ecosystem of cancer microenvironment.