Some assembly required: the development of neuronal synapses.
Li, Zheng, and Morgan Sheng. 2003. “Some Assembly Required: The Development of Neuronal Synapses.”. Nature Reviews. Molecular Cell Biology 4 (11): 833-41.
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Neurobiology: synapses unplugged.
Littleton, Troy, and Morgan Sheng. 2003. “Neurobiology: Synapses Unplugged.”. Nature 423 (6943): 931-2.
Interaction of the deafness-dystonia protein DDP/TIMM8a with the signal transduction adaptor molecule STAM1.
Blackstone, Craig, Roland G Roberts, Daniel P Seeburg, and Morgan Sheng. 2003. “Interaction of the Deafness-Dystonia Protein DDP/TIMM8a With the Signal Transduction Adaptor Molecule STAM1.”. Biochemical and Biophysical Research Communications 305 (2): 345-52.
Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes.
Fuhrmann, Jens C, Stefan Kins, Philippe Rostaing, Oussama El Far, Joachim Kirsch, Morgan Sheng, Antoine Triller, Heinrich Betz, and Matthias Kneussel. 2002. “Gephyrin Interacts With Dynein Light Chains 1 and 2, Components of Motor Protein Complexes.”. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 22 (13): 5393-402.
PDZ domains: structural modules for protein complex assembly.
Hung, Albert Y, and Morgan Sheng. 2002. “PDZ Domains: Structural Modules for Protein Complex Assembly.”. The Journal of Biological Chemistry 277 (8): 5699-702.
GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models.
Hanson, Jesse E, Keran Ma, Justin Elstrott, Martin Weber, Sandrine Saillet, Abdullah S Khan, Jeffrey Simms, et al. 2020. “GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer’s Disease Models.”. Cell Reports 30 (2): 381-396.e4.
Microglia in Brain Development, Homeostasis, and Neurodegeneration.
Bohlen, Christopher J, Brad A Friedman, Borislav Dejanovic, and Morgan Sheng. 2019. “Microglia in Brain Development, Homeostasis, and Neurodegeneration.”. Annual Review of Genetics 53: 263-88.
Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation.
Chang, Michael C, Karpagam Srinivasan, Brad A Friedman, Eric Suto, Zora Modrusan, Wyne P Lee, Joshua S Kaminker, David Hansen V, and Morgan Sheng. 2017. “Progranulin Deficiency Causes Impairment of Autophagy and TDP-43 Accumulation.”. The Journal of Experimental Medicine 214 (9): 2611-28.
TREM2, Microglia, and Neurodegenerative Diseases.
Yeh, Felix L, David Hansen V, and Morgan Sheng. 2017. “TREM2, Microglia, and Neurodegenerative Diseases.”. Trends in Molecular Medicine 23 (6): 512-33.
The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy.
Bingol, Baris, Joy S Tea, Lilian Phu, Mike Reichelt, Corey E Bakalarski, Qinghua Song, Oded Foreman, Donald S Kirkpatrick, and Morgan Sheng. 2014. “The Mitochondrial Deubiquitinase USP30 Opposes Parkin-Mediated Mitophagy.”. Nature 510 (7505): 370-5.