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Dolores Velit Soluta Nemo

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Impedit aliquid quas asperiores similique et. Dolores minus non qui deserunt. Sit Minima Eveniet Iusto Error. Quaerat eligendi occaecati nesciunt totam totam. Est ut commodi officiis. Dolor minus illo. Magnam eaque rerum suscipit sequi quae quisquam possimus. Rerum ipsum harum. Ea esse quis...

Fei Chen, Ph.D.

Person:

Core Institute Member, Broad Institute

Brian Liau, Ph.D.

Person:

Associate Professor of Chemistry and Chemical Biology, Harvard University

Proline-rich tyrosine kinase 2 regulates hippocampal long-term depression.

Publication: Journal Article

Hsin, Honor, Myung Jong Kim, Chi-Fong Wang, and Morgan Sheng. 2010. “Proline-Rich Tyrosine Kinase 2 Regulates Hippocampal Long-Term Depression.”. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 30 (36): 11983-93.

Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines.

Publication: Journal Article

Bingol, Baris, Chi-Fong Wang, David Arnott, Dongmei Cheng, Junmin Peng, and Morgan Sheng. 2010. “Autophosphorylated CaMKIIalpha Acts As a Scaffold to Recruit Proteasomes to Dendritic Spines.”. Cell 140 (4): 567-78.

Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes.

Publication: Journal Article

Hoogenraad, Casper C, Ioana Popa, Kensuke Futai, Emma Martinez-Sanchez, Phebe S Wulf, Thijs van Vlijmen, Bjorn R Dortland, et al. 2010. “Neuron Specific Rab4 Effector GRASP-1 Coordinates Membrane Specialization and Maturation of Recycling Endosomes.”. PLoS Biology 8 (1): e1000283.

Regulated RalBP1 binding to RalA and PSD-95 controls AMPA receptor endocytosis and LTD.

Publication: Journal Article

Han, Kihoon, Myoung-Hwan Kim, Daniel Seeburg, Jinsoo Seo, Chiara Verpelli, Seungnam Han, Hye Sun Chung, et al. 2009. “Regulated RalBP1 Binding to RalA and PSD-95 Controls AMPA Receptor Endocytosis and LTD.”. PLoS Biology 7 (9): e1000187.

A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-alpha.

Publication: Journal Article

Dickinson, Bryony A, Jihoon Jo, Heon Seok, Gi Hoon Son, Daniel J Whitcomb, Ceri H Davies, Morgan Sheng, Graham L Collingridge, and Kwangwook Cho. 2009. “A Novel Mechanism of Hippocampal LTD Involving Muscarinic Receptor-Triggered Interactions Between AMPARs, GRIP and Liprin-Alpha.”. Molecular Brain 2: 18.

Critical role of CDK5 and Polo-like kinase 2 in homeostatic synaptic plasticity during elevated activity.

Publication: Journal Article

Seeburg, Daniel P, Monica Feliu-Mojer, Johanna Gaiottino, Daniel T S Pak, and Morgan Sheng. 2008. “Critical Role of CDK5 and Polo-Like Kinase 2 in Homeostatic Synaptic Plasticity During Elevated Activity.”. Neuron 58 (4): 571-83.

Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.

Publication: Journal Article

Hung, Albert Y, Kensuke Futai, Carlo Sala, Juli G Valtschanoff, Jubin Ryu, Mollie A Woodworth, Fleur L Kidd, et al. 2008. “Smaller Dendritic Spines, Weaker Synaptic Transmission, But Enhanced Spatial Learning in Mice Lacking Shank1.”. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 28 (7): 1697-708.