Katie Irish
Operations Specialist, GRO
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Siddarth Wekhande
Computational Associate II, GRO
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Morgan Sheng, M.D., Ph.D.
he/him
Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broad’s Stanley Center for Psychiatric Research and Head of Stanley Center Therapeutics. email: msheng AT broadinstitute DOT org
Photoselective sequencing: microscopically guided genomic measurements with subcellular resolution.
Mangiameli, Sarah M, Haiqi Chen, Andrew S Earl, Julie A Dobkin, Daniel Lesman, Jason D Buenrostro, and Fei Chen. 2023. “Photoselective Sequencing: Microscopically Guided Genomic Measurements With Subcellular Resolution.”. Nature Methods 20 (5): 686-94.
A transcription factor atlas of directed differentiation.
Joung, Julia, Sai Ma, Tristan Tay, Kathryn R Geiger-Schuller, Paul C Kirchgatterer, Vanessa K Verdine, Baolin Guo, et al. 2023. “A Transcription Factor Atlas of Directed Differentiation.”. Cell 186 (1): 209-229.e26.
The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models.
Rozowsky, Joel, Jiahao Gao, Beatrice Borsari, Yucheng T Yang, Timur Galeev, Gamze Gürsoy, Charles B Epstein, et al. 2023. “The EN-TEx Resource of Multi-Tissue Personal Epigenomes & Variant-Impact Models.”. Cell 186 (7): 1493-1511.e40.
Human genetic diversity alters off-target outcomes of therapeutic gene editing.
Cancellieri, Samuele, Jing Zeng, Linda Yingqi Lin, Manuel Tognon, My Anh Nguyen, Jiecong Lin, Nicola Bombieri, et al. 2023. “Human Genetic Diversity Alters Off-Target Outcomes of Therapeutic Gene Editing.”. Nature Genetics 55 (1): 34-43.
Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin.
Ma, Sai, Bing Zhang, Lindsay M LaFave, Andrew S Earl, Zachary Chiang, Yan Hu, Jiarui Ding, et al. 2020. “Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin.”. Cell 183 (4): 1103-1116.e20.
Recruiting
Labs within the GRO are often hiring! Check out each GRO Investigator's profile to find a link to their lab page for more information. The team based at the Broad Institute is often hiring as well. You can search for open positions here.