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Meet the Researchers: Silvia Minardi, PhD

News: June 02, 2020
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Prabhat Kunwar, Ph.D.

he/him
Person: Senior Group Leader
Prabhat Kunwar is a senior group leader in the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard. His research focuses on understanding the neural circuit mechanisms underlying mental illnesses and translating those discoveries into novel therapeutics. His team’s...

Morgan Sheng, M.D., Ph.D.

he/him
Person:
Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broad’s Stanley Center for Psychiatric Research and Head of Stanley Center Therapeutics. email: msheng AT broadinstitute DOT org

Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.

Publication: Journal Article
Meilandt, William J, Hai Ngu, Alvin Gogineni, Guita Lalehzadeh, Seung-Hye Lee, Karpagam Srinivasan, Jose Imperio, et al. 2020. “Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aβ42:Aβ40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer’s Mouse Model.”. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience 40 (9): 1956-74.