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84 results found

The DNA architectural protein HMGB1 facilitates RTA-mediated viral gene expression in gamma-2 herpesviruses.

Publication: Journal Article

Song, Moon Jung, Seungmin Hwang, Wendy Wong, June Round, DeeAnn Martinez-Guzman, Yaron Turpaz, Jie Liang, et al. 2004. “The DNA Architectural Protein HMGB1 Facilitates RTA-Mediated Viral Gene Expression in Gamma-2 Herpesviruses.”. Journal of Virology 78 (23): 12940-50.

Kaposi's sarcoma-associated herpesvirus open reading frame 50 represses p53-induced transcriptional activity and apoptosis.

Publication: Journal Article

Gwack, Y, S Hwang, H Byun, C Lim, J W Kim, E J Choi, and J Choe. 2001. “Kaposi’s Sarcoma-Associated Herpesvirus Open Reading Frame 50 Represses P53-Induced Transcriptional Activity and Apoptosis.”. Journal of Virology 75 (13): 6245-8.

Nondegradative role of Atg5-Atg12/ Atg16L1 autophagy protein complex in antiviral activity of interferon gamma.

Publication: Journal Article

Hwang, Seungmin, Nicole S Maloney, Monique W Bruinsma, Gautam Goel, Erning Duan, Lei Zhang, Bimmi Shrestha, et al. 2012. “Nondegradative Role of Atg5-Atg12/ Atg16L1 Autophagy Protein Complex in Antiviral Activity of Interferon Gamma.”. Cell Host & Microbe 11 (4): 397-409.

Autophagy links inflammasomes to atherosclerotic progression.

Publication: Journal Article

Razani, Babak, Chu Feng, Trey Coleman, Roy Emanuel, Haitao Wen, Seungmin Hwang, Jenny P Ting, Herbert W Virgin, Michael B Kastan, and Clay F Semenkovich. 2012. “Autophagy Links Inflammasomes to Atherosclerotic Progression.”. Cell Metabolism 15 (4): 534-44.

Induction of protective immunity against murine gammaherpesvirus 68 infection in the absence of viral latency.

Publication: Journal Article

Jia, Qingmei, Michael L Freeman, Eric J Yager, Ian McHardy, Leming Tong, DeeAnn Martinez-Guzman, Tammy Rickabaugh, et al. 2010. “Induction of Protective Immunity Against Murine Gammaherpesvirus 68 Infection in the Absence of Viral Latency.”. Journal of Virology 84 (5): 2453-65.

Autophagy and Inflammation.

Publication: Journal Article

Matsuzawa-Ishimoto, Yu, Seungmin Hwang, and Ken Cadwell. 2018. “Autophagy and Inflammation.”. Annual Review of Immunology 36: 73-101.

Le Liu

Person: Visiting Graduate Student

I am a graduate student from the University of Massachusetts Amherst. I am fascinated by applying high-throughput imaging analysis to understand biological questions. It is a great opportunity for me to learn advanced software and machine learning methods!

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News: July 21, 2022

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Peter Winter

Person: Principal Investigator, Co-Director Ex Vivo, Broad Institute

Peter Winter, PhD Peter is a Principal Investigator at the Broad Institute of MIT and Harvard. He leads a multidisciplinary team that aims to understand how diverse facets of cancer biology (e.g. oncogenic mutations, RNA-state, and the microenvironment) cooperate to drive systems-level tumor...