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Tech R&D Projects

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Building on the team’s expertise in developing algorithms and user-friendly software for use in biology under real-world conditions, the Center will focus on two Technology Research and Development (TR&D) projects: (1) deep learning-based image processing, and (2) workflows and accessibility of...

Dr. Marvin Caruthers Receives the Inaugural Merkin Prize in Biomedical Technology in a Ceremony at The Broad Institute of MIT and Harvard

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FOR IMMEDIATE RELEASE CONTACT David Cameron, Broad Institute dcameron@broadinstitute.org 617-714-7184 Janet Janjigian, Carmen Group janjigianj@carmengroup.com 424-354-0133 Merkin Prize honors Dr. Caruthers’ transformative work synthesizing DNA September 27, 2023 (Cambridge, MA.)—Dr. Richard Merkin...

News & Events

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October 31, 2025 Carl June, Bruce Levine, Isabelle Rivière, and Michel Sadelain receive the 2025 Merkin Prize at the Broad Institute for chimeric antigen receptor (CAR) T-cell therapy Produced by the Heritage Provider Network video team This groundbreaking form of personalized cancer immunotherapy...

An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing.

Publication: Journal Article

Waterbury, Amanda L, Hui Si Kwok, Ceejay Lee, Domenic N Narducci, Allyson M Freedy, Cindy Su, Shaunak Raval, et al. 2024. “An Autoinhibitory Switch of the LSD1 Disordered Region Controls Enhancer Silencing.”. Molecular Cell 84 (12): 2238-2254.e11.

Dissection of a CTCF topological boundary uncovers principles of enhancer-oncogene regulation.

Publication: Journal Article

Kim, Kyung Lock, Gilbert J Rahme, Viraat Y Goel, Chadi A El Farran, Anders S Hansen, and Bradley E Bernstein. 2024. “Dissection of a CTCF Topological Boundary Uncovers Principles of Enhancer-Oncogene Regulation.”. Molecular Cell 84 (7): 1365-1376.e7.

Editor's Note: Androgen-Induced Differentiation and Tumorigenicity of Human Prostate Epithelial Cells

Publication: Journal Article

Berger, Raanan, Phillip G. Febbo, Pradip K. Majumder, Jean J. Zhao, Shayan Mukherjee, Sabina Signoretti, Thirza Campbell, et al. 2024. “Editor’s Note: Androgen-Induced Differentiation and Tumorigenicity of Human Prostate Epithelial Cells”. Cancer Research.

Alines Lebron-Torres

Person: Research Associate I

2024 Merkin Prize in Biomedical Technology awarded to F. William Studier for T7 Technology [VIDEO]

News: July 25, 2024

F. William Studier of Brookhaven National Laboratory has won the 2024 Richard N. Merkin Prize in Biomedical Technology for his development of an efficient, scalable method of producing RNA and proteins in the laboratory. His T7 expression technology can be used to make large quantities of nearly any...

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