Autophagy and Noroviruses.
Furlong, Kevin, and Seungmin Hwang. 2019. “Autophagy and Noroviruses.”. Viruses 11 (3).
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Molecular chaperone Hsp90 is a therapeutic target for noroviruses.
Vashist, Surender, Luis Urena, Mariam B Gonzalez-Hernandez, Jayoung Choi, Alexis de Rougemont, Joana Rocha-Pereira, Johan Neyts, Seungmin Hwang, Christiane E Wobus, and Ian Goodfellow. 2015. “Molecular Chaperone Hsp90 Is a Therapeutic Target for Noroviruses.”. Journal of Virology 89 (12): 6352-63.
BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models.
Rauh, Ulrike, Guo Wei, Michael Serrano-Wu, Georgios Kosmidis, Stefan Kaulfuss, Franziska Siegel, Kai Thede, et al. 2024. “BRD-810 Is a Highly Selective MCL1 Inhibitor With Optimized in Vivo Clearance and Robust Efficacy in Solid and Hematological Tumor Models.”. Nat Cancer.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Klionsky, Daniel J, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, et al. 2021. “Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th Edition)1.”. Autophagy 17 (1): 1-382.
Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock.
Finethy, Ryan, Jacob Dockterman, Miriam Kutsch, Nichole Orench-Rivera, Graham D Wallace, Anthony S Piro, Sarah Luoma, et al. 2020. “Dynamin-Related Irgm Proteins Modulate LPS-Induced Caspase-11 Activation and Septic Shock.”. EMBO Reports 21 (11): e50830.
Nucleotide triphosphatase and RNA chaperone activities of murine norovirus NS3.
Han, Kang Rok, Ji-Hye Lee, Giri Gowda Kotiguda, Kyoung Ho Jung, Mi Sook Chung, Soowon Kang, Seungmin Hwang, and Kyung Hyun Kim. 2018. “Nucleotide Triphosphatase and RNA Chaperone Activities of Murine Norovirus NS3.”. The Journal of General Virology 99 (11): 1482-93.
Partners in anti-crime: how interferon-inducible GTPases and autophagy proteins team up in cell-intrinsic host defense.
Coers, Jörn, Hailey M Brown, Seungmin Hwang, and Gregory A Taylor. 2018. “Partners in Anti-Crime: How Interferon-Inducible GTPases and Autophagy Proteins Team up in Cell-Intrinsic Host Defense.”. Current Opinion in Immunology 54: 93-101.
Demarcation of Viral Shelters Results in Destruction by Membranolytic GTPases: Antiviral Function of Autophagy Proteins and Interferon-Inducible GTPases.
Brown, Hailey M, Scott B Biering, Allen Zhu, Jayoung Choi, and Seungmin Hwang. 2018. “Demarcation of Viral Shelters Results in Destruction by Membranolytic GTPases: Antiviral Function of Autophagy Proteins and Interferon-Inducible GTPases.”. BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology 40 (6): e1700231.
Regulation of cell proliferation and migration by p62 through stabilization of Twist1.
Qiang, Lei, Baozhong Zhao, Mei Ming, Ning Wang, Tong-Chuan He, Seungmin Hwang, Andrew Thorburn, and Yu-Ying He. 2014. “Regulation of Cell Proliferation and Migration by P62 through Stabilization of Twist1.”. Proceedings of the National Academy of Sciences of the United States of America 111 (25): 9241-6.
Murine norovirus: propagation, quantification, and genetic manipulation.
Hwang, Seungmin, Bader Alhatlani, Armando Arias, Sarah L Caddy, Constantina Christodoulou, Juliana Bragazza Cunha, Ed Emmott, et al. 2014. “Murine Norovirus: Propagation, Quantification, and Genetic Manipulation.”. Current Protocols in Microbiology 33: 15K.2.1-61.