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Ava Amini

Person: Senior Researcher, Co-Director Ex Vivo, Microsoft Research

Ava Amini PhD Ava Amini is a senior researcher at Microsoft Research in Cambridge, MA. Her research focuses on engineering new technologies for precision medicine and has spanned machine learning, bioengineering, and cancer biology. Ava completed her PhD in Biophysics at Harvard University and the...

Data Access Request for Researchers

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Information for Researchers: If you need access to the drive, please fill out this form: ABIGNET Access Request form If you want to get in contact with the site managers of each country, please find their email information below: India: jayantmahadevan@gmail.com Pakistan: ahassan@broadinstitute.org...

The Francisella O-antigen mediates survival in the macrophage cytosol via autophagy avoidance.

Publication: Journal Article

Case, Elizabeth Di Russo, Audrey Chong, Tara D Wehrly, Bryan Hansen, Robert Child, Seungmin Hwang, Herbert W Virgin, and Jean Celli. 2014. “The Francisella O-Antigen Mediates Survival in the Macrophage Cytosol via Autophagy Avoidance.”. Cellular Microbiology 16 (6): 862-77.

TANK-binding kinase-1 plays an important role during in vitro and in vivo type I IFN responses to DNA virus infections.

Publication: Journal Article

Miyahira, Andrea K, Arash Shahangian, Seungmin Hwang, Ren Sun, and Genhong Cheng. 2009. “TANK-Binding Kinase-1 Plays an Important Role During in Vitro and in Vivo Type I IFN Responses to DNA Virus Infections.”. Journal of Immunology (Baltimore, Md. : 1950) 182 (4): 2248-57.

High-resolution functional profiling of a gammaherpesvirus RTA locus in the context of the viral genome.

Publication: Journal Article

Arumugaswami, Vaithilingaraja, Ronika Sitapara, Seungmin Hwang, Moon Jung Song, Tuyet Ngoc Ho, Nancy Qi Su, Eric Y Sue, et al. 2009. “High-Resolution Functional Profiling of a Gammaherpesvirus RTA Locus in the Context of the Viral Genome.”. Journal of Virology 83 (4): 1811-22.

Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 RTA reactivates murine gammaherpesvirus 68 from latency.

Publication: Journal Article

Rickabaugh, Tammy M, Helen J Brown, Ting-Ting Wu, Moon Jung Song, Seungmin Hwang, Hongyu Deng, Katherine Mitsouras, and Ren Sun. 2005. “Kaposi’s Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 RTA Reactivates Murine Gammaherpesvirus 68 from Latency.”. Journal of Virology 79 (5): 3217-22.

The Kaposi's sarcoma-associated herpesvirus K8 protein interacts with CREB-binding protein (CBP) and represses CBP-mediated transcription.

Publication: Journal Article

Hwang, S, Y Gwack, H Byun, C Lim, and J Choe. 2001. “The Kaposi’s Sarcoma-Associated Herpesvirus K8 Protein Interacts With CREB-Binding Protein (CBP) and Represses CBP-Mediated Transcription.”. Journal of Virology 75 (19): 9509-16.

Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway.

Publication: Journal Article

Chong, Audrey, Tara D Wehrly, Robert Child, Bryan Hansen, Seungmin Hwang, Herbert W Virgin, and Jean Celli. 2012. “Cytosolic Clearance of Replication-Deficient Mutants Reveals Francisella Tularensis Interactions With the Autophagic Pathway.”. Autophagy 8 (9): 1342-56.

Guidelines for the use and interpretation of assays for monitoring autophagy.

Publication: Journal Article

Klionsky, Daniel J, Fabio C Abdalla, Hagai Abeliovich, Robert T Abraham, Abraham Acevedo-Arozena, Khosrow Adeli, Lotta Agholme, et al. 2012. “Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy.”. Autophagy 8 (4): 445-544.

Robust and durable prophylactic protection conferred by RNA interference in preclinical models of SARS-CoV-2

Publication: Journal Article

Anglero-Rodriguez, Yesseinia I., Florian A. Lempp, James McIninch, Mark K. Schlegel, Christopher R. Brown, Donald J. Foster, Adam B. Castoreno, et al. 2022. “Robust and Durable Prophylactic Protection Conferred by RNA Interference in Preclinical Models of SARS-CoV-2”. BioRxiv.