Punctuated evolution of prostate cancer genomes
Baca, S. C., D. Prandi, M. S. Lawrence, J. M. Mosquera, A. Romanel, Y. Drier, K. Park, et al. 2013. “Punctuated Evolution of Prostate Cancer Genomes”. Cell 153: 666-77.
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A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity
Bachovchin, D. A., L. W. Koblan, W. Wu, Y. Liu, Y. Li, P. Zhao, I. Woznica, et al. 2014. “A High-Throughput, Multiplexed Assay for Superfamily-Wide Profiling of Enzyme Activity”. Nat Chem Biol 10: 656-63.
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Barretina, J., G. Caponigro, N. Stransky, K. Venkatesan, A. A. Margolin, S. Kim, C. J. Wilson, et al. 2019. “Addendum: The Cancer Cell Line Encyclopedia Enables Predictive Modelling of Anticancer Drug Sensitivity”. Nature 565: E5-E6.
Melanoma genome sequencing reveals frequent PREX2 mutations
Berger, M. F., E. Hodis, T. P. Heffernan, Y. L. Deribe, M. S. Lawrence, A. Protopopov, E. Ivanova, et al. 2012. “Melanoma Genome Sequencing Reveals Frequent PREX2 Mutations”. Nature 485: 502-6.
The genomic complexity of primary human prostate cancer
Berger, M. F., M. S. Lawrence, F. Demichelis, Y. Drier, K. Cibulskis, A. Y. Sivachenko, A. Sboner, et al. 2011. “The Genomic Complexity of Primary Human Prostate Cancer”. Nature 470: 214-20.
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
Bhattacharjee, A., W. G. Richards, J. Staunton, C. Li, S. Monti, P. Vasa, C. Ladd, et al. 2001. “Classification of Human Lung Carcinomas by MRNA Expression Profiling Reveals Distinct Adenocarcinoma Subclasses”. Proc Natl Acad Sci U S A 98: 13790-5.
Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes
Chapuy, B., C. Stewart, A. J. Dunford, J. Kim, A. Kamburov, R. A. Redd, M. S. Lawrence, et al. 2018. “Author Correction: Molecular Subtypes of Diffuse Large B Cell Lymphoma Are Associated With Distinct Pathogenic Mechanisms and Outcomes”. Nat Med 24: 1290-91.
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells
Chen, C. Z., M. Li, D. Graaf, S. Monti, B. Gottgens, M. J. Sanchez, E. S. Lander, T. R. Golub, A. R. Green, and H. F. Lodish. 2002. “Identification of Endoglin As a Functional Marker That Defines Long-Term Repopulating Hematopoietic Stem Cells”. Proc Natl Acad Sci U S A 99: 15468-73.
Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF
Du, J., H. R. Widlund, M. A. Horstmann, S. Ramaswamy, K. Ross, W. E. Huber, E. K. Nishimura, T. R. Golub, and D. E. Fisher. 2004. “Critical Role of CDK2 for Melanoma Growth Linked to Its Melanocyte-Specific Transcriptional Regulation by MITF”. Cancer Cell 6: 565-76.
Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy
Dvela-Levitt, M., M. Kost-Alimova, M. Emani, E. Kohnert, R. Thompson, E. H. Sidhom, A. Rivadeneira, et al. 2019. “Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy”. Cell 178: 521-535 e23.