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A CellProfiler Approach to Analyzing Tissue Data

Kyle Karhohs Imaging tissue slices provides a wealth of data about the spatial composition and number of the various cell types that make up a tissue. Interactions among cells within a tissue are crucial to understanding the role of the inflammation that is triggered by the invasion of cancerous...

Tracking projects with Gmail tags: Collaborating through email

Anne Carpenter As the PI of the Carpenter lab (a.k.a. Broad Institute Imaging Platform, including the CellProfiler team), people often ask how I manage so many ongoing collaborations: we discuss 50+ external projects each year so it is a lot to track! I am happy to reveal our secrets. The goal First...

Z-score big! A game plan for image-based profiling

Juan Caicedo As described in our lab’s recent review article, there are so many great reasons to use microscopy images to create signatures of perturbations: identifying phenotypes associated with disease, identifying chemical mechanisms of action, and discovering gene functions, among others. Have...

Welcome to the CellProfiler Blog!

CellProfiler Team The CellProfiler team is excited to announce the launch of our new blog! Articles will have a variety of topics, ranging from general knowledge, to specific module use and relevant literature spotlights. At the CellProfiler Forum, we answer all kinds of questions straight from the...

Getting Started with CellProfiler in Batch

Guest Author This post was written by a guest author, Jillian Rowe, who can be reached at jillian@dabbleofdevops.com. Running CellProfiler in batch mode is the ideal way to automate large scale analyses. Or not so large scale analyses that you prefer to automate! One of the benefits of running...

New CellProfiler 4 Plugin: RunCellpose

David R. Stirling Hi everyone, Today we’re releasing the RunCellpose plugin for CellProfiler 4! This plugin is designed to allow you to use the popular Cellpose segmentation algorithm to generate object sets within a CellProfiler pipeline. Cellpose uses a neural network followed by post-processing...

Making it easy to share the CRediT on your collaborative research projects

Beth Cimini In the Imaging Platform, we tend to work on a lot of big, complicated projects , with a lot of moving pieces and sometimes collaborators in many countries! This is fantastic for science, but when it comes to writing a paper, it can make just gathering all the information about "who did...

Announcing CellProfiler 3.1.8

Beth Cimini Happy holidays to everyone- we here at the CellProfiler team got you a little end-of-year treat in the form of CellProfiler 3.1.8. This is primarily a bugfix release, getting rid of some bugs in MeasureObjectIntensity, MeasureColocalization, ExportToSpreadsheet...