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What We Do

Through the collaborative development and dissemination of open source image analysis software, as well as training events and resources, the Center will empower thousands of researchers to apply advanced analytics in innovative ways to address new experimental areas.

Collaborate

Need help with image analysis? The first step is to post in the Scientific Community Image Forum under the COBA tag. The COBA team and members of the community can help answer questions, so this is a great resource for most of your imaging analysis problems If posting there doesn't answer your...

More info

Frequently Asked Questions (FAQ) Is it too late to join? Yes, the Consortium has finished its work optimizing, producing data, and publicly releasing it. There are two new Consortia to consider: OASIS (‘Omics for Assessing Signatures for Integrated Safety): Together with HESI, we aim to test Cell...

Data Transfer

Sequencing data produced by the Broad CMG will be made available to collaborators upon request with the required contingency that phenotype information is entered on seqr. Please note we are only able to return data to the investigator that initiated this collaboration, as well as relevant study...

Press from the Imaging Platform (Carpenter-Singh and Cimini labs)

Impact of CellProfiler on human health Our CellProfiler software has yielded discoveries in several translational projects, some of which may ultimately have a direct impact on the treatment of disease [ read more here]. Public videos of talks and PDF slides Links to PDFs of slides from recent talks...

Papers

For our latest work, check out our preprints on bioRxiv! ( Carpenter) ( Singh) Google Scholar pages (with citation metrics): ( Carpenter) ( Singh) 212. Rouquié D, Bender A, Cheah J, Crute C, Dalmas D, Ewald J, Fullerton A, Harrill JA, Kadri S, Kleinstreuer N, Kramer N, LaRocca J, Mitchell CA, Seal S...

Human MCF7 cells – compound-profiling experiment

Accession number BBBC021 · Version 1 Example Images Actin disrupter Aurora kinase inhbitor Eg5 inhibitor Tubulin destabilizer Tubulin stabilizer Description of the biological application Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each...

Human U2OS cells – Gene overexpression profiling experiment

Accession number BBBC037 · Version 1 Example images Description of the biological application The image set can be used to functionally annotate the genes through comparing their overexpression morphological profiles. Images Images from five fluorescent channels were captured at 20x magnification on...