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Human U2OS cells – Small molecule Cell Painting experiment

Accession number BBBC040 · Version 1 Example images Biological application An ideal small-molecule screening library would be enriched in non-redundant bioactive compounds that maximize the performance diversity of the library. The construction of such libraries would be aided by a rapid feedback...

Nuclei of mouse embryonic cells

Accession number BBBC050 · Version 2 Example images Biological application Cell dynamics during the early mouse embryogenesis change spatiotemporally. For understanding the mechanism of this developmental process, imaging cell dynamics by live-cell imaging of fluorescently labeled nuclei and...

Resources

After seven wonderful years at the Broad Institute (2016-2023), I have started a new exciting career journey in Madison, WI. Our research group is now at the Morgridge Institute for Research and the University of Wisconsin—Madison. Learn more: https://morgridge.org/research/labs/caicedo/...

Cell Painting

The Carpenter lab and Schreiber lab at the Broad Institute of MIT and Harvard developed Cell Painting, a microscopy assay that generates images that reflect cell response to treatments such as drug or genetic perturbations, in high-throughput (at a scale of 100,000+ perturbations). The Carpenter lab...

Research

KIDNEY DISEASE Autosomal dominant MUC1 kidney disease (MKD, also known as ADTKD-MUC1, and formerly called MCKD1) is a rare hereditary renal disease that ultimately requires dialysis or kidney transplantation for patients. For decades, scientists had known the genetic “neighborhood” of the mutation...

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Labs within the GRO are often hiring! Check out each GRO Investigator's profile to find a link to their lab page for more information. The team based at the Broad Institute is often hiring as well. You can search for open positions here.