Kasper Lage, Ph.D., M.B.A.
Managing Director of the Novo Nordisk Foundation Center, Broad Institute Director of Bioinformatics at the Department of Surgery, Massachusetts General Hospital Associate Professor, Harvard Medical School
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Neva Cherniavsky Durand, Ph.D.
Senior Scientist, GRO
Amrita Sule, Ph.D.
Research Scientist II, GRO and dGTEx
Global identification of SWI/SNF targets reveals compensation by EP400.
Martin, Benjamin J E, Eileen F Ablondi, Christine Goglia, Claudia A Mimoso, Piero R Espinel-Cabrera, and Karen Adelman. 2023. “Global Identification of SWI/SNF Targets Reveals Compensation by EP400.”. Cell.
Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements.
Hu, Yan, Sai Ma, Vinay K Kartha, Fabiana M Duarte, Max Horlbeck, Ruochi Zhang, Rojesh Shrestha, et al. 2023. “Single-Cell Multi-Scale Footprinting Reveals the Modular Organization of DNA Regulatory Elements.”. BioRxiv : The Preprint Server for Biology.
Massively parallel base editing to map variant effects in human hematopoiesis.
Martin-Rufino, Jorge D, Nicole Castano, Michael Pang, Emanuelle I Grody, Samantha Joubran, Alexis Caulier, Lara Wahlster, et al. 2023. “Massively Parallel Base Editing to Map Variant Effects in Human Hematopoiesis.”. Cell 186 (11): 2456-2474.e24.
Jason Buenrostro named a 2023 MacArthur Fellow
Our GRO Co-Director Jason Buenrostro is named in the 2023 cohort of MacArthur Genius Grant Fellows, in recognition of his impact in tool and technology development thus far, and for his ongoing research in gene regulation and cellular function. Check out his MacArthur Foundation bio here, and an...
An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing.
Waterbury, Amanda L, Hui Si Kwok, Ceejay Lee, Domenic N Narducci, Allyson M Freedy, Cindy Su, Shaunak Raval, et al. 2024. “An Autoinhibitory Switch of the LSD1 Disordered Region Controls Enhancer Silencing.”. Molecular Cell 84 (12): 2238-2254.e11.
Dissection of a CTCF topological boundary uncovers principles of enhancer-oncogene regulation.
Kim, Kyung Lock, Gilbert J Rahme, Viraat Y Goel, Chadi A El Farran, Anders S Hansen, and Bradley E Bernstein. 2024. “Dissection of a CTCF Topological Boundary Uncovers Principles of Enhancer-Oncogene Regulation.”. Molecular Cell 84 (7): 1365-1376.e7.
Vijay Sankaran, M.D., Ph.D.
Jan Ellen Paradise, MD Professor of Pediatrics, Harvard Medical School Investigator, Howard Hughes Medical Institute Attending Physician, Dana-Farber/Boston Children's Cancer and Blood Disorders Center