Search
Search results
32 results found
"From Genes to Mechanisms to Medicines: The Arc of Discovery for Kidney Diseases" by Anna Greka, MD, PhD
Talk description text here.
Sean P Moran, Ph.D.
Sean Moran is a neuropharmacologist with a strong passion for translational neuroscience research who earned his PhD from Vanderbilt University under the mentorship of P. Jeffrey Conn. During his graduate training at the Vanderbilt Center for Neuroscience Drug Discovery, Sean utilized molecular...
Papers
For our latest work, check out our preprints on bioRxiv! ( Carpenter) ( Singh) Google Scholar pages (with citation metrics): ( Carpenter) ( Singh) 204. Seal S, Mahale M, García-Ortegón M, Joshi CK, Hosseini-Gerami L, Beatson A, Greenig M, Shekhar M, Patra A, Weis C, Mehrjou A, Badré A, Paisley B...
Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome
McCamphill, Patrick, Laura Stoppel, Rebecca Senter, Michael Lewis, Arnold Heynen, David Stoppel, Vinay Sridhar, et al. 2020. “Selective Inhibition of Glycogen Synthase Kinase 3α Corrects Pathophysiology in a Mouse Model of Fragile X Syndrome”. Science Translational Medicine 12 (544).
Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia
Wagner, Florence, Lina Benajiba, Arthur Campbell, Michel We{\"ıwer, Joshua Sacher, Jennifer Gale, Linda Ross, et al. 2018. “Exploiting an Asp-Glu ‘switch’ in Glycogen Synthase Kinase 3 to Design Paralog-Selective Inhibitors for Use in Acute Myeloid Leukemia”. Science Translational Medicine 10 (431).
Overexpression of NEUROG2 and NEUROG1 in human embryonic stem cells produces a network of excitatory and inhibitory neurons
Lu, Congyi, Xi Shi, Andrew Allen, David Baez-Nieto, Alexandria Nikish, Neville Sanjana, and Jen Pan. 2019. “Overexpression of NEUROG2 and NEUROG1 in Human Embryonic Stem Cells Produces a Network of Excitatory and Inhibitory Neurons”. The FASEB Journal 33 (4): 5287–5299.
Acoustic tweezers for the life sciences
Ozcelik, Adem, Joseph Rufo, Feng Guo, Yuyang Gu, Peng Li, James Lata, and Tony Jun Huang. 2018. “Acoustic Tweezers for the Life Sciences”. Nature Methods 15 (12): 1021–1028.
Research
KIDNEY DISEASE Autosomal dominant MUC1 kidney disease (MKD, also known as ADTKD-MUC1, and formerly called MCKD1) is a rare hereditary renal disease that ultimately requires dialysis or kidney transplantation for patients. For decades, scientists had known the genetic “neighborhood” of the mutation...
James Coleman, B.S.
Before graduating from Northeastern University in May 2020 with a BS in behavioral neuroscience, James was involved in research studying sleep, memory and pharmacology using both neuroimaging and electrophysiological approaches. His undergraduate thesis was on the neurological and behavioral effects...