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Rat astrocyte cells

Accession number BBBC042 · Version 1 Example images Description of the biological application The morphology of astrocytes is highly heterogeneous and counting them is currently a laborious task. Development of fully automated counting methods for astrocytes from immunohistological images without...

Mouse hippocampal presynaptic terminals (vGlut-1 and vGat)

Accession number BBBC044 · Version 1 Example images Description of the biological application These images are of mouse hippocampal presynaptic terminals and the goal is to extract presynaptic terminals' densities. The presented seet of images were being used to validate the accuracy of automatic...

Human White Blood Cells

Accession number BBBC045 · Version 1 Example images Description of the biological application This dataset is useful for measuring differential White Blood Cell Count. White blood cells play an important role in the immune system to protect against infections and diseases. There are 5 different...

Human HT29 colon-cancer cells shRNAi screen

Accession number BBBC017 · Version 1 Example image Biological application These images are of human HT29 colon cancer cells, a cell line that has been widely used for the study of many normal and neoplastic processes. Moffat et al. (Cell, 2006) used the HT29 cell line to screen 4,903 shRNAi...

Human U2OS Cells – profiling bioactive compounds using Cell Painting

Accession number BBBC036 · Version 1 Example images Description of the biological application Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each sample so that similarities between profiles reflect similarities between samples. This...

Impact on Human Health

Our CellProfiler software has yielded discoveries in several translational projects, some of which have had a direct impact on the treatment of disease. For example, CellProfiler has been used to identify several small molecules that are effective in treating particular diseases in mouse models. In...

Image Sets

Identification and segmentation Accession Description Mode Fields per Sample Total Fields Total Images Ground Truth BBBC001 Human HT29 colon-cancer cells Fluorescent 6 6 6 BBBC002 Drosophila Kc167 cells Fluorescent 5 50 50 BBBC003 Mouse embryos DIC 15 15 15 BBBC004 Synthetic cells Fluorescent 20 100...

Synthetic cells

Accession number BBBC005 · Version 1 Example images In focus Out of focus True foreground Biological application Since robust foreground/background separation and segmentation of cellular objects (i.e.,identification of which pixels below to which objects) strongly depends on image quality, focus...