The genomic complexity of primary human prostate cancer
Berger, M. F., M. S. Lawrence, F. Demichelis, Y. Drier, K. Cibulskis, A. Y. Sivachenko, A. Sboner, et al. 2011. “The Genomic Complexity of Primary Human Prostate Cancer”. Nature 470: 214-20.
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Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
Bhattacharjee, A., W. G. Richards, J. Staunton, C. Li, S. Monti, P. Vasa, C. Ladd, et al. 2001. “Classification of Human Lung Carcinomas by MRNA Expression Profiling Reveals Distinct Adenocarcinoma Subclasses”. Proc Natl Acad Sci U S A 98: 13790-5.
Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes
Chapuy, B., C. Stewart, A. J. Dunford, J. Kim, A. Kamburov, R. A. Redd, M. S. Lawrence, et al. 2018. “Author Correction: Molecular Subtypes of Diffuse Large B Cell Lymphoma Are Associated With Distinct Pathogenic Mechanisms and Outcomes”. Nat Med 24: 1290-91.
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells
Chen, C. Z., M. Li, D. Graaf, S. Monti, B. Gottgens, M. J. Sanchez, E. S. Lander, T. R. Golub, A. R. Green, and H. F. Lodish. 2002. “Identification of Endoglin As a Functional Marker That Defines Long-Term Repopulating Hematopoietic Stem Cells”. Proc Natl Acad Sci U S A 99: 15468-73.
Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF
Du, J., H. R. Widlund, M. A. Horstmann, S. Ramaswamy, K. Ross, W. E. Huber, E. K. Nishimura, T. R. Golub, and D. E. Fisher. 2004. “Critical Role of CDK2 for Melanoma Growth Linked to Its Melanocyte-Specific Transcriptional Regulation by MITF”. Cancer Cell 6: 565-76.
Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy
Dvela-Levitt, M., M. Kost-Alimova, M. Emani, E. Kohnert, R. Thompson, E. H. Sidhom, A. Rivadeneira, et al. 2019. “Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy”. Cell 178: 521-535 e23.
c-Myc is a critical target for c/EBPalpha in granulopoiesis
Johansen, L. M., A. Iwama, T. A. Lodie, K. Sasaki, D. W. Felsher, T. R. Golub, and D. G. Tenen. 2001. “C-Myc Is a Critical Target for C/EBPalpha in Granulopoiesis”. Mol Cell Biol 21: 3789-806.
LACTB is a tumour suppressor that modulates lipid metabolism and cell state
Keckesova, Z., J. L. Donaher, J. De Cock, E. Freinkman, S. Lingrell, D. A. Bachovchin, B. Bierie, et al. 2017. “LACTB Is a Tumour Suppressor That Modulates Lipid Metabolism and Cell State”. Nature 543: 681-86.
Impaired microRNA processing enhances cellular transformation and tumorigenesis
Kumar, M. S., J. Lu, K. L. Mercer, T. R. Golub, and T. Jacks. 2007. “Impaired MicroRNA Processing Enhances Cellular Transformation and Tumorigenesis”. Nat Genet 39: 673-7.
Mutational heterogeneity in cancer and the search for new cancer-associated genes
Lawrence, M. S., P. Stojanov, P. Polak, G. V. Kryukov, K. Cibulskis, A. Sivachenko, S. L. Carter, et al. 2013. “Mutational Heterogeneity in Cancer and the Search for New Cancer-Associated Genes”. Nature 499: 214-18.