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NSF BBSRC Imaging Flow Cytometry Project

NSF BBSRC Imaging Flow Cytometry Project (July 15, 2015–June 30, 2018) [ Project abstract at nsf.gov] [Project Outcomes Report (search here, using Fed Award ID 1458626 ( PDF))] Non-technical description of the problem: There are a variety of cell types circulating in human blood, each with distinct...

Promo Images

Biographical images are available here with credits noted in each folder name. Permission to use those or any images on this page must be requested via imagingadmin@broadinstitute.org.

Software and code

DeepProfiler DeepProfiler is a set of tools that allow you to use deep learning for analyzing imaging data in high-throughput biological experiments. Documentation and instructions for DeepProfiler can be found in our Handbook and the code is located on the GitHub page. Cytominer The Pycytominer...

Shantanu Singh

I lead the image-based profiling team. We develop machine learning and statistical methods to create fingerprints of genes, chemicals, and diseases from microscopy images of cells.

Papers

For our latest work, check out our preprints on bioRxiv! ( Carpenter) ( Singh) Google Scholar pages (with citation metrics): ( Carpenter) ( Singh) 198. Seal S, Trapotsi MA, Spjuth O, Singh S, Carreras-Puigvert J, Greene N, Bender A, Carpenter AE. (2024) Cell Painting: a decade of discovery and...

Press from the Imaging Platform (Carpenter-Singh and Cimini labs)

Impact of CellProfiler on human health Our CellProfiler software has yielded discoveries in several translational projects, some of which may ultimately have a direct impact on the treatment of disease [ read more here]. Public videos of talks and PDF slides Links to PDFs of slides from recent talks...

Education and Outreach

You can download teaching materials related to our group's research at the CellProfiler website here.

Funding

Since 2003, grants have been provided by... ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​

Lab Policy and Culture

Photo credit: Juliana Sohn Our mission & ethos: Our mission is to uncover biological knowledge and new medicines by developing advanced methods to quantify and mine the rich information in images. Together, our team explores the inner workings of biological systems and makes discoveries that can...