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Disease Areas of Focus
Retinal Inherited retinal degenerations (IRDs) are characterized by progressive dysfunction and death of rod and cone photoreceptor cells, leading to vision loss, and are one of the most genetically diverse groups of inherited disorders. Identifying the genetic cause of patients’ IRD has become...
Community Enagagment
COBA’s mission is to catalyze the entire bioimage analysis software community. What have we accomplished thus far? Scientific Community Image Forum We created and sponsor the Scientific Community Image Forum. This forum has brought together dozens of open source image analysis platforms to one...
Cite Us
How to cite CellProfiler in publications (the project's survival depends on it!) CellProfiler for cells (feel free to cite the most recent) : Stirling DR, Swain-Bowden MJ, Lucas AM, Carpenter AE, Cimini BA, Goodman A (2021). CellProfiler 4: improvements in speed, utility and usability. BMC...
Software and code
CellProfiler and CellProfiler Analyst Our lab previously launched and led the CellProfiler and CellProfiler Analyst projects, beloved by biologists around the world for bioimage analysis and cited over 15,000 times. They are now developed and maintained by the Cimini lab (since 2021). DeepProfiler ...
An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndrome
Ebert, B. L., N. Galili, P. Tamayo, J. Bosco, R. Mak, J. Pretz, S. Tanguturi, et al. 2008. “An Erythroid Differentiation Signature Predicts Response to Lenalidomide in Myelodysplastic Syndrome”. PLoS Med 5: e35.
Cas9 activates the p53 pathway and selects for p53-inactivating mutations
Enache, O. M., V. Rendo, M. Abdusamad, D. Lam, D. Davison, S. Pal, N. Currimjee, et al. 2020. “Cas9 Activates the P53 Pathway and Selects for P53-Inactivating Mutations”. Nat Genet 52: 662-68.
Author Correction: Cas9 activates the p53 pathway and selects for p53-inactivating mutations
Enache, O. M., V. Rendo, M. Abdusamad, D. Lam, D. Davison, S. Pal, N. Currimjee, et al. 2020. “Author Correction: Cas9 Activates the P53 Pathway and Selects for P53-Inactivating Mutations”. Nat Genet 52: 748-49.
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
Ferrando, A. A., D. S. Neuberg, J. Staunton, M. L. Loh, C. Huard, S. C. Raimondi, F. G. Behm, et al. 2002. “Gene Expression Signatures Define Novel Oncogenic Pathways in T Cell Acute Lymphoblastic Leukemia”. Cancer Cell 1: 75-87.