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Morgan Sheng, M.D., Ph.D.

he/him

Person:

Morgan Sheng is a core institute member of the Broad Institute of MIT and Harvard, where he serves as co-director of the Broad’s Stanley Center for Psychiatric Research and Head of Stanley Center Therapeutics. email: msheng AT broadinstitute DOT org

Photoselective sequencing: microscopically guided genomic measurements with subcellular resolution.

Publication: Journal Article

Mangiameli, Sarah M, Haiqi Chen, Andrew S Earl, Julie A Dobkin, Daniel Lesman, Jason D Buenrostro, and Fei Chen. 2023. “Photoselective Sequencing: Microscopically Guided Genomic Measurements With Subcellular Resolution.”. Nature Methods 20 (5): 686-94.

A transcription factor atlas of directed differentiation.

Publication: Journal Article

Joung, Julia, Sai Ma, Tristan Tay, Kathryn R Geiger-Schuller, Paul C Kirchgatterer, Vanessa K Verdine, Baolin Guo, et al. 2023. “A Transcription Factor Atlas of Directed Differentiation.”. Cell 186 (1): 209-229.e26.

The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models.

Publication: Journal Article

Rozowsky, Joel, Jiahao Gao, Beatrice Borsari, Yucheng T Yang, Timur Galeev, Gamze Gürsoy, Charles B Epstein, et al. 2023. “The EN-TEx Resource of Multi-Tissue Personal Epigenomes & Variant-Impact Models.”. Cell 186 (7): 1493-1511.e40.

Human genetic diversity alters off-target outcomes of therapeutic gene editing.

Publication: Journal Article

Cancellieri, Samuele, Jing Zeng, Linda Yingqi Lin, Manuel Tognon, My Anh Nguyen, Jiecong Lin, Nicola Bombieri, et al. 2023. “Human Genetic Diversity Alters Off-Target Outcomes of Therapeutic Gene Editing.”. Nature Genetics 55 (1): 34-43.

Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin.

Publication: Journal Article

Ma, Sai, Bing Zhang, Lindsay M LaFave, Andrew S Earl, Zachary Chiang, Yan Hu, Jiarui Ding, et al. 2020. “Chromatin Potential Identified by Shared Single-Cell Profiling of RNA and Chromatin.”. Cell 183 (4): 1103-1116.e20.

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Eric S. Lander, Ph.D.

Person:

Core Institute Member & Founding Director, Broad Institute Professor, Department of Biology, MIT Professor of Systems Biology, Harvard Medical School

Eugenio Mattei, Ph.D.

Person:

Senior Computational Scientist I GRO, Broad Institute

Nina Farrell, MPS, PMP

Person:

Project Manager II