Kasper Lage, Ph.D., M.B.A.
Managing Director of the Novo Nordisk Foundation Center, Broad Institute Director of Bioinformatics at the Department of Surgery, Massachusetts General Hospital Associate Professor, Harvard Medical School
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437 results found
Neva Cherniavsky Durand, Ph.D.
Senior Scientist, GRO
Amrita Sule, Ph.D.
Research Scientist II, GRO and dGTEx
Sizing up whole-brain neuronal tracing
Ascoli, Giorgio A., Bing-Xing Huo, and Partha P. Mitra. 2022. “Sizing up Whole-Brain Neuronal Tracing”. Science Bulletin 67 (9).
Semantic segmentation of microscopic neuroanatomical data by combining topological priors with encoder-decoder deep networks.
Banerjee, Samik, Lucas Magee, Dingkang Wang, Xu Li, Bing-Xing Huo, Jaikishan Jayakumar, Katherine Matho, et al. 2020. “Semantic Segmentation of Microscopic Neuroanatomical Data by Combining Topological Priors With Encoder-Decoder Deep Networks.”. Nature Machine Intelligence 2 (10): 585-94.
Brief anesthesia, but not voluntary locomotion, significantly alters cortical temperature.
Shirey, Michael J, Jared B Smith, D’Anne E Kudlik, Bing-Xing Huo, Stephanie E Greene, and Patrick J Drew. 2015. “Brief Anesthesia, But Not Voluntary Locomotion, Significantly Alters Cortical Temperature.”. Journal of Neurophysiology 114 (1): 309-22.
Single duplex DNA sequencing with CODEC detects mutations with high sensitivity
Bae, Jin H., Ruolin Liu, Eugenia Roberts, Erica Nguyen, Shervin Tabrizi, Justin Rhoades, Timothy Blewett, et al. 2023. “Single Duplex DNA Sequencing With CODEC Detects Mutations With High Sensitivity”. Nat Genet.
Global identification of SWI/SNF targets reveals compensation by EP400.
Martin, Benjamin J E, Eileen F Ablondi, Christine Goglia, Claudia A Mimoso, Piero R Espinel-Cabrera, and Karen Adelman. 2023. “Global Identification of SWI/SNF Targets Reveals Compensation by EP400.”. Cell.
Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements.
Hu, Yan, Sai Ma, Vinay K Kartha, Fabiana M Duarte, Max Horlbeck, Ruochi Zhang, Rojesh Shrestha, et al. 2023. “Single-Cell Multi-Scale Footprinting Reveals the Modular Organization of DNA Regulatory Elements.”. BioRxiv : The Preprint Server for Biology.
Massively parallel base editing to map variant effects in human hematopoiesis.
Martin-Rufino, Jorge D, Nicole Castano, Michael Pang, Emanuelle I Grody, Samantha Joubran, Alexis Caulier, Lara Wahlster, et al. 2023. “Massively Parallel Base Editing to Map Variant Effects in Human Hematopoiesis.”. Cell 186 (11): 2456-2474.e24.