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LC3s hire membrane breakers to attack viral shelters.

Publication: Journal Article

Biering, Scott B, Jayoung Choi, Hailey M Brown, and Seungmin Hwang. 2017. “LC3s Hire Membrane Breakers to Attack Viral Shelters.”. Autophagy 13 (11): 2010-12.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Publication: Journal Article

Klionsky, Daniel J, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Abraham Acevedo Arozena, Hiroaki Adachi, et al. 2016. “Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition).”. Autophagy 12 (1): 1-222.

Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages.

Publication: Journal Article

Kratz, Mario, Brittney R Coats, Katherine B Hisert, Derek Hagman, Vesco Mutskov, Eduard Peris, Kelly Q Schoenfelt, et al. 2014. “Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages.”. Cell Metabolism 20 (4): 614-25.

Project Ex Vivo

Project Ex Vivo is a groundbreaking collaboration between Microsoft Research and the Broad Institute. We harness the power of AI and machine learning to guide our cancer research. This initiative aims to define, engineer, and target cell states in cancer, driving innovative advancements in precision oncology.

News Headline 6

News: July 21, 2022

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Srivatsan Raghavan

Person: Assistant Professor, Co-Director Ex Vivo, Harvard Medical School

Srivatsan Raghavan, MD/PhD Dr. Srivatsan Raghavan, MD, PhD, is a medical oncologist and physician-scientist at the Dana-Farber Cancer Institute and Brigham and Women’s Hospital and an Instructor in Medicine at Harvard Medical School. He specializes in the clinical care of patients with...

The Francisella O-antigen mediates survival in the macrophage cytosol via autophagy avoidance.

Publication: Journal Article

Case, Elizabeth Di Russo, Audrey Chong, Tara D Wehrly, Bryan Hansen, Robert Child, Seungmin Hwang, Herbert W Virgin, and Jean Celli. 2014. “The Francisella O-Antigen Mediates Survival in the Macrophage Cytosol via Autophagy Avoidance.”. Cellular Microbiology 16 (6): 862-77.

TANK-binding kinase-1 plays an important role during in vitro and in vivo type I IFN responses to DNA virus infections.

Publication: Journal Article

Miyahira, Andrea K, Arash Shahangian, Seungmin Hwang, Ren Sun, and Genhong Cheng. 2009. “TANK-Binding Kinase-1 Plays an Important Role During in Vitro and in Vivo Type I IFN Responses to DNA Virus Infections.”. Journal of Immunology (Baltimore, Md. : 1950) 182 (4): 2248-57.

High-resolution functional profiling of a gammaherpesvirus RTA locus in the context of the viral genome.

Publication: Journal Article

Arumugaswami, Vaithilingaraja, Ronika Sitapara, Seungmin Hwang, Moon Jung Song, Tuyet Ngoc Ho, Nancy Qi Su, Eric Y Sue, et al. 2009. “High-Resolution Functional Profiling of a Gammaherpesvirus RTA Locus in the Context of the Viral Genome.”. Journal of Virology 83 (4): 1811-22.

Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 RTA reactivates murine gammaherpesvirus 68 from latency.

Publication: Journal Article

Rickabaugh, Tammy M, Helen J Brown, Ting-Ting Wu, Moon Jung Song, Seungmin Hwang, Hongyu Deng, Katherine Mitsouras, and Ren Sun. 2005. “Kaposi’s Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 RTA Reactivates Murine Gammaherpesvirus 68 from Latency.”. Journal of Virology 79 (5): 3217-22.