The genomic landscape of pediatric Ewing sarcoma
Crompton, B. D., C. Stewart, A. Taylor-Weiner, G. Alexe, K. C. Kurek, M. L. Calicchio, A. Kiezun, et al. 2014. “The Genomic Landscape of Pediatric Ewing Sarcoma”. Cancer Discov 4: 1326-41.
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Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy
Du, J., P. Bernasconi, K. R. Clauser, D. R. Mani, S. P. Finn, R. Beroukhim, M. Burns, et al. 2009. “Bead-Based Profiling of Tyrosine Kinase Phosphorylation Identifies SRC As a Potential Target for Glioblastoma Therapy”. Nat Biotechnol 27: 77-83.
LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures
Duan, Q., C. Flynn, M. Niepel, M. Hafner, J. L. Muhlich, N. F. Fernandez, A. D. Rouillard, et al. 2014. “LINCS Canvas Browser: Interactive Web App to Query, Browse and Interrogate LINCS L1000 Gene Expression Signatures”. Nucleic Acids Res 42: W449-60.
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry
Durbin, A. D., M. W. Zimmerman, N. V. Dharia, B. J. Abraham, A. B. Iniguez, N. Weichert-Leahey, S. He, et al. 2018. “Selective Gene Dependencies in MYCN-Amplified Neuroblastoma Include the Core Transcriptional Regulatory Circuitry”. Nat Genet 50: 1240-46.
DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis
Okondo, M. C., D. C. Johnson, R. Sridharan, E. B. Go, A. J. Chui, M. S. Wang, S. E. Poplawski, et al. 2017. “DPP8 and DPP9 Inhibition Induces Pro-Caspase-1-Dependent Monocyte and Macrophage Pyroptosis”. Nat Chem Biol 13: 46-53.
p210BCR/ABL, p190BCR/ABL, and TEL/ABL activate similar signal transduction pathways in hematopoietic cell lines
Okuda, K., T. R. Golub, D. G. Gilliland, and J. D. Griffin. 1996. “P210BCR/ABL, P190BCR/ABL, and TEL/ABL Activate Similar Signal Transduction Pathways in Hematopoietic Cell Lines”. Oncogene 13: 1147-52.
IFN-alpha-stimulated genes and Epstein-Barr virus gene expression distinguish WHO type II and III nasopharyngeal carcinomas
Pegtel, D. M., A. Subramanian, D. Meritt, C. H. Tsai, T. S. Sheen, T. R. Golub, and D. A. Thorley-Lawson. 2007. “IFN-Alpha-Stimulated Genes and Epstein-Barr Virus Gene Expression Distinguish WHO Type II and III Nasopharyngeal Carcinomas”. Cancer Res 67: 474-81.
The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation
Peng, T., T. R. Golub, and D. M. Sabatini. 2002. “The Immunosuppressant Rapamycin Mimics a Starvation-Like Signal Distinct from Amino Acid and Glucose Deprivation”. Mol Cell Biol 22: 5575-84.
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer
Polak, P., J. Kim, L. Z. Braunstein, R. Karlic, N. J. Haradhavala, G. Tiao, D. Rosebrock, et al. 2017. “A Mutational Signature Reveals Alterations Underlying Deficient Homologous Recombination Repair in Breast Cancer”. Nat Genet 49: 1476-86.
DNA microarrays in clinical oncology
Ramaswamy, S., and T. R. Golub. 2002. “DNA Microarrays in Clinical Oncology”. J Clin Oncol 20: 1932-41.