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Benchmarking algorithms for gene regulatory network inference from single-cell transcriptomic data

Publication: Journal Article

Pratapa, Aditya, Amogh Jalihal, Jeffrey Law, Aditya Bharadwaj, and Murali. 2020. “Benchmarking Algorithms for Gene Regulatory Network Inference from Single-Cell Transcriptomic Data”. Nat Methods 17 (2): 147-54.

Fast-SL: an efficient algorithm to identify synthetic lethal sets in metabolic networks

Publication: Journal Article

Pratapa, Aditya, Shankar Balachandran, and Karthik Raman. 2015. “Fast-SL: an Efficient Algorithm to Identify Synthetic Lethal Sets in Metabolic Networks”. Bioinformatics 31 (20): 3299-305.

Photo credit: Martin Adolfsson Associate Professor Harvard Medical School Brigham and Women’s Hospital Institute Member Director Kidney Disease Initiative Broad Institute of MIT and Harvard With a focus on laying the foundation for molecularly targeted therapies, Anna’s scientific work is centered...

Published: "Open-source deep-learning software for bioimage segmentation"

News: April 19, 2021

American Society for Cell Biology journal Molecular Biology of the Cell published a manuscript from COBA researchers surveying several new open-source software tools that aim to make deep-learning–based image segmentation accessible to biologists with limited computational experience. Read the paper...

Free online image analysis workshop for beginners!

News: April 26, 2021

June 24: This interactive workshop will focus on adapting CellProfiler pipelines to new datasets. Undergrad / early grad students will be prioritized, but all are welcome. Sign up (space limited): http://broad.io/cellprofilerworkshopsignup. This course will be jointly led by Julia van den Beemd and...

Anne Carpenter Awarded American Society for Cell Biology’s Women in Cell Biology Mid-career Award

News: November 30, 2020

COBA's Anne Carpenter recently won the American Society for Cell Biology's Women in Cell Biology Mid-career Award. As part of this award, Carpenter wrote an award essay, "A well-engineered path into cell biology and academia", published in the November 30 issue of Molecular Biology of the Cell. Of...

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Anna Greka Katie Liguori Administrative Assistant kliguori@broadinstitute.org Matthew Racette Lab Manager mracette@broadinstitute.org Jillian Shaw Scientific Advisor Juan Lorenzo Pablo Senior Scientist Masha Alimova Senior Scientist Nicolas Wieder Keith Keller Silvana Bazua Valeria Padovano Julie...

Anne Carpenter featured on two podcasts: "Theory and Practice" and "The Microscopists"

News: April 08, 2021

Today, two podcasts featuring Anne Carpenter were released. On Google Ventures' Theory and Practice season two, Carpenter spoke with Google Ventures' Anthony Philippakis and Alex Wiltschko from Google AI, focusing on machine learning in drug discovery. The full episode is available below. On The...

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