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Vladimir Tkachev

Person: Research Associate I

Vladimir graduated from the University of New Hampshire in the spring of 2022 with a major in Neuroscience and Behavior and a minor in Biomedical Sciences. During his undergraduate years, Vladimir conducted research in the Neurobiology lab of Dr. Arturo Andrade and Immunology lab of Dr. Sherine...

Sean P Moran, Ph.D.

Person: Research Scientist II

Sean Moran is a neuropharmacologist with a strong passion for translational neuroscience research who earned his PhD from Vanderbilt University under the mentorship of P. Jeffrey Conn. During his graduate training at the Vanderbilt Center for Neuroscience Drug Discovery, Sean utilized molecular...

Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction

Publication: Journal Article

Shi, Xi. 2021. “Heterozygous Deletion of the Autism-Associated Gene CHD8 Impairs Synaptic Function through Widespread Changes in Gene Expression and Chromatin Compaction”. American Journal of Human Genetics.

Mouse mutants in schizophrenia risk genes GRIN2A and AKAP11 show EEG abnormalities in common with schizophrenia patients

Publication: Journal Article

Herzog, Linnea E. 2023. “Mouse Mutants in Schizophrenia Risk Genes GRIN2A and AKAP11 Show EEG Abnormalities in Common With Schizophrenia Patients”. Translational Psychiatry.

IntelliSleepScorer, a software package with a graphic user interface for automated sleep stage scoring in mice based on a light gradient boosting machine algorithm.

Publication: Manuscript

Wang, Lei A. 2023. “IntelliSleepScorer, a Software Package With a Graphic User Interface for Automated Sleep Stage Scoring in Mice Based on a Light Gradient Boosting Machine Algorithm..”

AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatology

Publication: Manuscript

Tsimberidou, Apostolia-Maria. 2022. “AKT Inhibition in the Central Nervous System Induces Signaling Defects Resulting in Psychiatric Symptomatology.”

Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome

Publication: Journal Article

Hwang, Hongik, Matthew J. Szucs, Lei J. Ding, Andrew Allen, Xiaobai Ren, Henny Haensgen, Fan Gao, et al. 2021. “Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome”. Biological Psychiatry 89 (3): 256-69.

Yining Wang

Person: Computational Associate I

Yining is a Computational Associate. She majored in Data Science and Computer Science.

Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome

Publication: Journal Article

McCamphill, Patrick, Laura Stoppel, Rebecca Senter, Michael Lewis, Arnold Heynen, David Stoppel, Vinay Sridhar, et al. 2020. “Selective Inhibition of Glycogen Synthase Kinase 3α Corrects Pathophysiology in a Mouse Model of Fragile X Syndrome”. Science Translational Medicine 12 (544).

Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia

Publication: Journal Article

Wagner, Florence, Lina Benajiba, Arthur Campbell, Michel We{\"ıwer, Joshua Sacher, Jennifer Gale, Linda Ross, et al. 2018. “Exploiting an Asp-Glu ‘switch’ in Glycogen Synthase Kinase 3 to Design Paralog-Selective Inhibitors for Use in Acute Myeloid Leukemia”. Science Translational Medicine 10 (431).