Eric S. Lander, Ph.D.
Core Institute Member & Founding Director, Broad Institute Professor, Department of Biology, MIT Professor of Systems Biology, Harvard Medical School
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103 results found
Eugenio Mattei, Ph.D.
Senior Computational Scientist I GRO, Broad Institute
Nina Farrell, MPS, PMP
Project Manager II
Brady Walker
Project Coordinator, GRO and dGTEx
Functional inference of gene regulation using single-cell multi-omics.
Kartha, Vinay K, Fabiana M Duarte, Yan Hu, Sai Ma, Jennifer G Chew, Caleb A Lareau, Andrew Earl, et al. 2022. “Functional Inference of Gene Regulation Using Single-Cell Multi-Omics.”. Cell Genomics 2 (9).
Drug addiction unveils a repressive methylation ceiling in EZH2-mutant lymphoma.
Kwok, Hui Si, Allyson M Freedy, Allison P Siegenfeld, Julia W Morriss, Amanda L Waterbury, Stephen M Kissler, and Brian B Liau. 2023. “Drug Addiction Unveils a Repressive Methylation Ceiling in EZH2-Mutant Lymphoma.”. Nature Chemical Biology.
Epigenetic clocks, aging, and cancer.
Johnstone, Sarah E, Vadim N Gladyshev, Martin J Aryee, and Bradley E Bernstein. 2022. “Epigenetic Clocks, Aging, and Cancer.”. Science (New York, N.Y.) 378 (6626): 1276-77.
Spatial genomics enables multi-modal study of clonal heterogeneity in tissues.
Zhao, Tongtong, Zachary D Chiang, Julia W Morriss, Lindsay M LaFave, Evan M Murray, Isabella Del Priore, Kevin Meli, et al. 2022. “Spatial Genomics Enables Multi-Modal Study of Clonal Heterogeneity in Tissues.”. Nature 601 (7891): 85-91.
Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging.
Gabriele, Michele, Hugo B Brandão, Simon Grosse-Holz, Asmita Jha, Gina M Dailey, Claudia Cattoglio, Tsung-Han S Hsieh, Leonid Mirny, Christoph Zechner, and Anders S Hansen. 2022. “Dynamics of CTCF- and Cohesin-Mediated Chromatin Looping Revealed by Live-Cell Imaging.”. Science (New York, N.Y.) 376 (6592): 496-501.
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