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The Carpenter lab and Schreiber lab at the Broad Institute of MIT and Harvard developed Cell Painting, a microscopy assay that generates images that reflect cell response to treatments such as drug or genetic perturbations, in high-throughput (at a scale of 100,000+ perturbations). The Carpenter lab...

KIDNEY DISEASE Autosomal dominant MUC1 kidney disease (MKD, also known as ADTKD-MUC1, and formerly called MCKD1) is a rare hereditary renal disease that ultimately requires dialysis or kidney transplantation for patients. For decades, scientists had known the genetic “neighborhood” of the mutation...